USP11 and LLGL1

Number of citations of the paper that reports this interaction (PubMedID 26919101)
14

Data Source:
BioGRID (affinity chromatography technology, pull down)

		USP11	LLGL1
Description		ubiquitin specific peptidase 11	LLGL scribble cell polarity complex component 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol	Golgi Cis Cisterna Cytoplasm Cytoskeleton Plasma Membrane Axon Cortical Actin Cytoskeleton Early Endosome Membrane Trans-Golgi Network Membrane
	Molecular Function	Transcription Corepressor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding	GTPase Activator Activity Structural Molecule Activity Protein Binding Protein Kinase Binding Myosin II Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination	Exocytosis Golgi To Plasma Membrane Transport Axonogenesis Regulation Of Notch Signaling Pathway Cortical Actin Cytoskeleton Organization Regulation Of Establishment Or Maintenance Of Cell Polarity Regulation Of Protein Secretion Regulation Of Catalytic Activity Establishment Of Spindle Orientation Protein-containing Complex Assembly
Pathways		Association of TriC/CCT with target proteins during biosynthesis Ub-specific processing proteases
Drugs
Diseases
GWAS			LDL cholesterol ( 30275531) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		22 interacting genes: BMI1 BRCA2 CBX8 CDKN1A DECR2 EIF4B LIMS1 LLGL1 MBD3 MTA2 NONO PCGF2 PML RANBP9 RELB RNF2 RPS6KB1 SETDB1 SUMO2 TBL3 TP53 UBC	6 interacting genes: ACD AGTR1 CACNA1A CD46 STX4 USP11
Entrez ID		8237	3996
HPRD ID		02081	02982
Ensembl ID		ENSG00000102226	ENSG00000131899
Uniprot IDs		B4DGK3 P51784	Q15334
PDB IDs		4MEL 5OK6
Enriched GO Terms of Interacting Partners?
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