LGALS8 and ITGA3

Number of citations of the paper that reports this interaction (PubMedID 10852818)
54

Data Source:
HPRD (in vivo, in vitro)

		LGALS8	ITGA3
Description		galectin 8	integrin subunit alpha 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle	Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Filopodium Membrane Integrin Alpha3-beta1 Complex Receptor Complex Perinuclear Region Of Cytoplasm Excitatory Synapse Extracellular Exosome Cell Periphery Synaptic Membrane Growth Cone Filopodium
	Molecular Function	Integrin Binding Protein Binding Carbohydrate Binding	Fibronectin Binding Protease Binding Integrin Binding Protein Binding Collagen Binding Protein Domain Specific Binding Laminin Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Cellular Response To Virus Xenophagy Lymphatic Endothelial Cell Migration	Neuron Migration Cell-matrix Adhesion Integrin-mediated Signaling Pathway Heart Development Memory Response To Xenobiotic Stimulus Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Wnt Signaling Pathway Lung Development Regulation Of BMP Signaling Pathway Negative Regulation Of Cell Projection Organization Response To Gonadotropin Negative Regulation Of Rho Protein Signal Transduction Exploration Behavior Skin Development Mesodermal Cell Differentiation Maternal Process Involved In Female Pregnancy Nephron Development Dendritic Spine Maintenance Renal Filtration Positive Regulation Of Protein Localization To Plasma Membrane
Pathways			Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions MET activates PTK2 signaling
Drugs
Diseases
GWAS		Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		21 interacting genes: APEH BARD1 CALCOCO2 ERBB2 ITGA3 ITGA4 ITGB1 LRRK2 MEFV MID2 NACC1 NR1D2 TAX1BP1 TNFRSF18 TRIM17 TRIM22 TRIM23 TRIM49 TRIM5 TRIM6 WBP2	15 interacting genes: ADAM9 BIN1 CALR CD151 CD82 CD9 FHL2 FN1 HPS5 HSPD1 ITGB1 LGALS8 RABIF TIMP2 TSPAN4
Entrez ID		3964	3675
HPRD ID		09356	05431
Ensembl ID		ENSG00000116977	ENSG00000005884
Uniprot IDs		O00214	A0A140VJM0 P26006
PDB IDs		2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4BMB 4BME 4FQZ 4GXL 4HAN 5GZC 5GZD 5GZE 5GZF 5GZG 5T7I 5T7S 5T7T 5T7U 5VWG 6W4Z 6Z6Y
Enriched GO Terms of Interacting Partners?
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