ITGA3 and CD151

Number of citations of the paper that reports this interaction (PubMedID 10734060)
55

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vivo)

		ITGA3	CD151
Description		integrin subunit alpha 3	CD151 molecule (Raph blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Filopodium Membrane Integrin Alpha3-beta1 Complex Receptor Complex Perinuclear Region Of Cytoplasm Excitatory Synapse Extracellular Exosome Cell Periphery Synaptic Membrane Growth Cone Filopodium	Basement Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane
	Molecular Function	Fibronectin Binding Protease Binding Integrin Binding Protein Binding Collagen Binding Protein Domain Specific Binding Laminin Binding Metal Ion Binding Protein Heterodimerization Activity	Integrin Binding Protein Binding
	Biological Process	Neuron Migration Cell-matrix Adhesion Integrin-mediated Signaling Pathway Heart Development Memory Response To Xenobiotic Stimulus Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Wnt Signaling Pathway Lung Development Regulation Of BMP Signaling Pathway Negative Regulation Of Cell Projection Organization Response To Gonadotropin Negative Regulation Of Rho Protein Signal Transduction Exploration Behavior Skin Development Mesodermal Cell Differentiation Maternal Process Involved In Female Pregnancy Nephron Development Dendritic Spine Maintenance Renal Filtration Positive Regulation Of Protein Localization To Plasma Membrane	Cell Adhesion Cell Migration Positive Regulation Of Cell Migration T Cell Proliferation Wound Healing, Spreading Of Cells Positive Regulation Of Endocytosis
Pathways		Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions MET activates PTK2 signaling	Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly
Drugs
Diseases
GWAS			Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)
Interacting Genes		15 interacting genes: ADAM9 BIN1 CALR CD151 CD82 CD9 FHL2 FN1 HPS5 HSPD1 ITGB1 LGALS8 RABIF TIMP2 TSPAN4	12 interacting genes: ARL13B BCL7A GRAMD1C ITGA3 ITGA6 ITGB1 KLRC1 MMP7 PTGFRN RNF128 TMEM139 TSPAN18
Entrez ID		3675	977
HPRD ID		05431	03763
Ensembl ID		ENSG00000005884	ENSG00000177697
Uniprot IDs		A0A140VJM0 P26006	A0A024RCB3 P48509 Q6ZNZ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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