SPN and PLP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPN	PLP2
Description		sialophorin	proteolipid protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Uropod Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Membrane PML Body Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Hsp70 Protein Binding Heat Shock Protein Binding	Protein Binding Ion Transmembrane Transporter Activity Chemokine Binding
	Biological Process	T-helper 1 Cell Lineage Commitment Chemotaxis Immune Response Cellular Defense Response Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Regulation Of Immune Response Leukocyte Tethering Or Rolling Regulation Of T Cell Migration Positive Regulation Of T Cell Migration	Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Ion Transmembrane Transport
Pathways		Cell surface interactions at the vascular wall Basigin interactions
Drugs
Diseases
GWAS			Platelet distribution width ( 32888494)
Interacting Genes		18 interacting genes: ARL13B CLCA4 CTNNB1 CTSA CXCL16 CYBC1 DAXX ERGIC3 EZR FYN ICAM1 LGALS1 LMNA MSN PLP2 SGTA SIGLEC1 UBQLN2	75 interacting genes: AQP2 AQP3 AQP8 ARFIP2 ASGR2 ATP5PF BCAP31 BIK BNIP3 CCR1 CD53 CD79A CERS4 CIAO2A CLDN5 CLN8 CPLX4 CRB3 CREB3L1 CYB561 CYBC1 CYBRD1 DARS2 DLGAP4 DNAJC1 EBP ELOVL5 ELP1 EVI2A FAM209A FAM210B FATE1 FCER1G FNDC9 GPR151 GPX8 HSBP1L1 HSD17B11 HSD17B13 KASH5 LHFPL1 LHFPL5 LMNA LRRC4C MGST3 NDRG4 PACC1 PDZK1IP1 PIGP PSCA PTGES PVR RAB10 REEP4 RETREG3 RNF5 SAR1A SCN3B SGPL1 SHBG SLC14A2 SLC18A1 SLC2A13 SLC35C2 SPG21 SPN THAP4 TM4SF19 TMEM14B TMEM31 TMEM51 TMEM79 TMPRSS2 TMX2 VKORC1
Entrez ID		6693	5355
HPRD ID		06770	02121
Ensembl ID		ENSG00000197471	ENSG00000102007
Uniprot IDs		A0A024R629 P16150	A0A024QYW3 Q04941
PDB IDs
Enriched GO Terms of Interacting Partners?
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