ACAT2 and DYNLT1

		ACAT2	DYNLT1
Description		acetyl-CoA acetyltransferase 2	dynein light chain Tctex-type 1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Extracellular Exosome	Extracellular Region Cytoplasm Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Acetyl-CoA C-acetyltransferase Activity Protein Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding Dynein Intermediate Chain Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Beta-oxidation	Establishment Of Mitotic Spindle Orientation Microtubule-based Movement Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways		Cholesterol biosynthesis	Neutrophil degranulation
Drugs		S-Hydroxycysteine Coenzyme A
Diseases
GWAS		Erosive tooth wear (severe vs non-severe) ( 29898447) Lipoprotein (a) levels ( 30108283)
Interacting Genes		8 interacting genes: AKT1 CDX2 CSNK2A1 DYNLT1 LNX1 TERF1 WWOX ZNF76	57 interacting genes: ACAT2 ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 CRHBP DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 ERO1A FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PRKN PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RPS6KA2 RRAGA SDCBP SIRPA SVIL SYNJ2 TCEANC TMEM143 TROAP TUBA3C TXN UXT VDAC1 XRN2
Entrez ID		39	6993
HPRD ID		00006	15987
Ensembl ID		ENSG00000120437	ENSG00000146425
Uniprot IDs		Q9BWD1	P63172
PDB IDs		1WL4 1WL5	5JPW
Enriched GO Terms of Interacting Partners?
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