AFF3 and DPP8

		AFF3	DPP8
Description		AF4/FMR2 family member 3	dipeptidyl peptidase 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Body Super Elongation Complex	Cytoplasm Cytosol
	Molecular Function	Double-stranded DNA Binding DNA-binding Transcription Factor Activity	Aminopeptidase Activity Protein Binding Serine-type Peptidase Activity Dipeptidyl-peptidase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Response To Tumor Necrosis Factor Embryonic Hindlimb Morphogenesis	Proteolysis Apoptotic Process Immune Response
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 27798627) Albumin-globulin ratio ( 29403010) Apolipoprotein A1 levels ( 32203549) Arthritis (juvenile idiopathic) ( 33106285) Asthma ( 34103634) Autoimmune traits (pleiotropy) ( 30572963) Body shape index ( 34021172) Cannabis dependence symptom count ( 27028160) Celiac disease ( 30572963) Celiac disease and Rheumatoid arthritis ( 26546613) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 34187846 31527586) General cognitive ability ( 29844566) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Height ( 31217584) Hip circumference adjusted for BMI ( 34021172) Household income ( 27818178) Household income (MTAG) ( 31844048) IgG levels ( 28628107) Immature fraction of reticulocytes ( 32888494) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29617998) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 27647854) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Multisite chronic pain ( 33830993) Non-albumin protein levels ( 29403010) Number of children ever born ( 27798627) Plateletcrit ( 32888494 27863252) Red blood cell count ( 27863252) Refractive astigmatism ( 30306274) Regular attendance at a religious group ( 29970889) Rheumatoid arthritis ( 30423114 24782177 30572963 23143596 24390342 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Serum total protein level ( 29403010) Triglyceride levels ( 34074324) Type 1 diabetes ( 25751624 17554260 34127860) Type 1 diabetes nephropathy ( 23028342) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Basophil percentage of white cells ( 32888494) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494 20139978) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Red blood cell count ( 29403010 32888494)
Interacting Genes		5 interacting genes: DPP8 GPR137B IL18R1 IL18RAP ST6GAL2	1 interacting genes: AFF3
Entrez ID		3899	54878
HPRD ID		03272	07076
Ensembl ID		ENSG00000144218	ENSG00000074603
Uniprot IDs		P51826 Q8NAP7	A0A024R5Z6 A8K4U2 B4DLA8 Q6V1X1
PDB IDs			6EOO 6EOP 6EOS 6EOT 6HP8 6QZW 6TRW 6TRX
Enriched GO Terms of Interacting Partners?
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