SMIM1 and NAALAD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMIM1	NAALAD2
Description		small integral membrane protein 1 (Vel blood group)	N-acetylated alpha-linked acidic dipeptidase 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Serine-type Peptidase Activity Dipeptidyl-peptidase Activity Dipeptidase Activity Metal Ion Binding
	Biological Process		Proteolysis
Pathways			Aspartate and asparagine metabolism
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Adult body size ( 32376654) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)
Interacting Genes		56 interacting genes: ANKS6 AQP6 ASZ1 BCL2L13 BIK CD74 CISD2 COMT CREB3L1 CYB561 EBP ERGIC3 FAM174A FAM209A FAM210B FCER1G FFAR2 FNDC9 GJA8 GJB5 HACD2 HSD17B13 ICAM3 JAGN1 KIR2DL3 LHFPL5 LRP10 LRRC4C MFF MFSD6 MUC1 NAALAD2 NDUFAF2 PVR REEP4 RELL2 RETREG3 SAR1A SCN3B SDC3 SIGLEC7 SLC10A6 SLC18A1 SLC26A11 STING1 STX1A TM4SF19 TMEM154 TMEM31 TMEM45B TMEM51 TMEM52B TMEM86B TMPRSS2 TMX2 ZDHHC15	4 interacting genes: CIDEB RHBDD2 SMIM1 SPCS1
Entrez ID		388588	10003
HPRD ID			07494
Ensembl ID		ENSG00000235169	ENSG00000077616
Uniprot IDs		B2RUZ4 M4WDD3	J3KNJ3 Q9Y3Q0
PDB IDs			3FEC 3FED 3FEE 3FF3
Enriched GO Terms of Interacting Partners?
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