KCNA4 and KCNA2

Number of citations of the paper that reports this interaction (PubMedID 10428084)
46

Data Source:
HPRD (in vitro, in vivo)

		KCNA4	KCNA2
Description		potassium voltage-gated channel subfamily A member 4	potassium voltage-gated channel subfamily A member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon Dendritic Spine	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Paranodal Junction Perikaryon Axon Terminus Juxtaparanode Region Of Axon Calyx Of Held Integral Component Of Presynaptic Membrane
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Ion Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Kinesin Binding
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Potassium Ion Transport Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Protein Homooligomerization Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Arginineamide Dalfampridine	Enflurane Promethazine Miconazole Dalfampridine
Diseases
GWAS		Adult body size ( 32376654) Diastolic blood pressure ( 27841878) Luteinizing hormone levels in polycystic ovary syndrome ( 26284813) Menarche (age at onset) ( 27182965) Polycystic ovary syndrome ( 26284813) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 27841878)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		17 interacting genes: ACTN2 CASK DLG1 DLG2 DLG3 DLG4 DLGAP1 ERBIN KCNA2 LNX1 NDUFA4L2 NEK2 NEU1 PATJ SAT1 SNTA1 SNTG1	16 interacting genes: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 FAM3C KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA
Entrez ID		3739	3737
HPRD ID		01444	01443
Ensembl ID		ENSG00000182255	ENSG00000177301
Uniprot IDs		P22459	P16389
PDB IDs
Enriched GO Terms of Interacting Partners?
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