KCNA2 and KCNAB1

Number of citations of the paper that reports this interaction (PubMedID 8636142)
43

Data Source:
HPRD (in vivo)

		KCNA2	KCNAB1
Description		potassium voltage-gated channel subfamily A member 2	potassium voltage-gated channel subfamily A regulatory beta subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Paranodal Junction Perikaryon Axon Terminus Juxtaparanode Region Of Axon Calyx Of Held Integral Component Of Presynaptic Membrane	Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Dendrite Cytoplasm Potassium Channel Complex Perikaryon Juxtaparanode Region Of Axon Proximal Dendrite
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Kinesin Binding	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Potassium Channel Regulator Activity Protein Domain Specific Binding Transmembrane Transporter Binding D-threo-aldose 1-dehydrogenase Activity NADPH Binding
	Biological Process	Potassium Ion Transport Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Protein Homooligomerization Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane	Potassium Ion Transport Brain Development Heart Development Skeletal Muscle Tissue Development Myoblast Differentiation Diaphragm Development Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Voltage-gated Potassium Channel Activity
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Dalfampridine	Enflurane Promethazine Miconazole
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Age-related nuclear cataracts ( 24951543) Aging traits ( 17903295) Coronary artery disease ( 26708285) Focal epilepsy (with hippocampal sclerosis) ( 30531953) Offspring birth weight ( 31043758)
Interacting Genes		16 interacting genes: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 FAM3C KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA	9 interacting genes: APP DLG1 FBXO7 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SRPK1
Entrez ID		3737	7881
HPRD ID		01443	03089
Ensembl ID		ENSG00000177301	ENSG00000169282
Uniprot IDs		P16389	B7Z435 B7Z8E5 F8W6W4 Q14722 Q5MJQ3
PDB IDs
Enriched GO Terms of Interacting Partners?
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