KCNA2 and KCNA4

Number of citations of the paper that reports this interaction (PubMedID 10428084)
46

Data Source:
HPRD (in vitro, in vivo)

		KCNA2	KCNA4
Description		potassium voltage-gated channel subfamily A member 2	potassium voltage-gated channel subfamily A member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Paranodal Junction Perikaryon Axon Terminus Juxtaparanode Region Of Axon Calyx Of Held Integral Component Of Presynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon Dendritic Spine
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Kinesin Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Ion Binding
	Biological Process	Potassium Ion Transport Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Optic Nerve Structural Organization Regulation Of Ion Transmembrane Transport Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Protein Homooligomerization Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Dalfampridine	Enflurane Promethazine Miconazole Arginineamide Dalfampridine
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Adult body size ( 32376654) Diastolic blood pressure ( 27841878) Luteinizing hormone levels in polycystic ovary syndrome ( 26284813) Menarche (age at onset) ( 27182965) Polycystic ovary syndrome ( 26284813) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 27841878)
Interacting Genes		16 interacting genes: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 FAM3C KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA	17 interacting genes: ACTN2 CASK DLG1 DLG2 DLG3 DLG4 DLGAP1 ERBIN KCNA2 LNX1 NDUFA4L2 NEK2 NEU1 PATJ SAT1 SNTA1 SNTG1
Entrez ID		3737	3739
HPRD ID		01443	01444
Ensembl ID		ENSG00000177301	ENSG00000182255
Uniprot IDs		P16389	P22459
PDB IDs
Enriched GO Terms of Interacting Partners?
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