IL1B and IL1R2

  • Number of citations of the paper that reports this interaction (PubMedID 7878046)
  • 53
  • Data Source:
  • HPRD (in vitro)

IL1B

IL1R2

Description interleukin 1 beta interleukin 1 receptor type 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Birth weight ( 31043758)
  • Dysmenorrheic pain severity ( 29855537)
  • Gestational age at birth (child effect) ( 31477735)
  • Post-term birth ( 31477735)
  • Ankylosing spondylitis ( 23749187 20062062)
  • Asthma ( 31619474)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood protein levels ( 30072576 29875488)
  • C-reactive protein levels ( 30388399)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Fibrinogen ( 23969696)
  • Fibrinogen levels ( 28107422)
  • Inflammatory bowel disease ( 28067908 23128233)
  • Parkinson's disease ( 32201043 28892059)
  • Ulcerative colitis ( 21297633)
Interacting Genes 17 interacting genes: A2M ADRB2 APP CASP1 CASP4 CMA1 EGR1 FURIN FYN IL1R1 IL1R2 IL1RAP LYN MMP2 NEDD4 PRTN3 SP1 5 interacting genes: IL1A IL1B IL1RAP IL1RN USP15
Entrez ID 3553 7850
HPRD ID 00985 00995
Ensembl ID ENSG00000125538 ENSG00000115590
Uniprot IDs P01584 P27930
PDB IDs 1HIB 1I1B 1IOB 1ITB 1L2H 1S0L 1T4Q 1TOO 1TP0 1TWE 1TWM 21BI 2I1B 2KH2 2NVH 31BI 3LTQ 3O4O 3POK 41BI 4DEP 4G6J 4G6M 4GAF 4GAI 4I1B 5BVP 5I1B 5MVZ 5R7W 5R85 5R86 5R87 5R88 5R89 5R8A 5R8B 5R8C 5R8D 5R8E 5R8F 5R8G 5R8H 5R8I 5R8J 5R8K 5R8L 5R8M 5R8N 5R8O 5R8P 5R8Q 6I1B 6Y8I 6Y8M 7CHY 7CHZ 7I1B 9ILB 3O4O
Enriched GO Terms of Interacting Partners?
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