IL1B and CASP1

  • Number of citations of the paper that reports this interaction (PubMedID 1919001)
  • 70
  • Data Source:
  • BioGRID (enzymatic study, enzymatic study, enzymatic study)
  • HPRD (in vivo, in vitro)

IL1B

CASP1

Description interleukin 1 beta caspase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Birth weight ( 31043758)
  • Dysmenorrheic pain severity ( 29855537)
  • Gestational age at birth (child effect) ( 31477735)
  • Post-term birth ( 31477735)
  • Hip circumference adjusted for BMI ( 28552196)
Interacting Genes 17 interacting genes: A2M ADRB2 APP CASP1 CASP4 CMA1 EGR1 FURIN FYN IL1R1 IL1R2 IL1RAP LYN MMP2 NEDD4 PRTN3 SP1 45 interacting genes: AR ATN1 ATXN3 BCAP31 BCL2L1 BID CARD16 CARD17 CARD8 CASP10 CASP14 CASP8 CAST CDK11B DRD2 EGFR FGF2 HTT HUWE1 IL18 IL1A IL1B IL33 IL37 LMNA MAPT NEDD4 NFE2L2 NLRC4 NLRP1 NOD1 PAK1 PARP1 PLA2G4A PLA2G4B PRKN PSEN1 PSEN2 PYCARD RIPK2 RNF31 SERPINB9 TFAP2A TIRAP VAC14
Entrez ID 3553 834
HPRD ID 00985 00977
Ensembl ID ENSG00000125538 ENSG00000137752
Uniprot IDs P01584 A8K249 A8K257 P29466
PDB IDs 1HIB 1I1B 1IOB 1ITB 1L2H 1S0L 1T4Q 1TOO 1TP0 1TWE 1TWM 21BI 2I1B 2KH2 2NVH 31BI 3LTQ 3O4O 3POK 41BI 4DEP 4G6J 4G6M 4GAF 4GAI 4I1B 5BVP 5I1B 5MVZ 5R7W 5R85 5R86 5R87 5R88 5R89 5R8A 5R8B 5R8C 5R8D 5R8E 5R8F 5R8G 5R8H 5R8I 5R8J 5R8K 5R8L 5R8M 5R8N 5R8O 5R8P 5R8Q 6I1B 6Y8I 6Y8M 7CHY 7CHZ 7I1B 9ILB 1BMQ 1IBC 1ICE 1RWK 1RWM 1RWN 1RWO 1RWP 1RWV 1RWW 1RWX 1SC1 1SC3 1SC4 2FQQ 2H48 2H4W 2H4Y 2H51 2H54 2HBQ 2HBR 2HBY 2HBZ 3D6F 3D6H 3D6M 3E4C 3NS7 5FNA 5MMV 5MTK 6BZ9 6F6R 6KN0 6PZP 6VIE 7KEU
Enriched GO Terms of Interacting Partners?
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