SERINC2 and TMEM54

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SERINC2	TMEM54
Description		serine incorporator 2	transmembrane protein 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane Extracellular Exosome	Cellular_component Integral Component Of Membrane
	Molecular Function		Molecular_function Protein Binding
	Biological Process	Phosphatidylserine Metabolic Process Sphingolipid Metabolic Process Positive Regulation Of CDP-diacylglycerol-serine O-phosphatidyltransferase Activity Positive Regulation Of Serine C-palmitoyltransferase Activity	Biological_process
Pathways		Serine biosynthesis
Drugs
Diseases
GWAS		Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heart rate response to recovery post exercise (50 sec) ( 29497042) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		16 interacting genes: C4orf3 CCDC167 GPX8 LAT MFF SEC22B SLC12A7 SLC29A2 SLC39A9 SMAGP TMEM14A TMEM167B TMEM239 TMEM42 TMEM54 TMEM86B	25 interacting genes: ARL13B CD3G CLSTN3 CREB3 FKBP7 GPR152 GPR37L1 HPCA KCNJ8 KCNK5 KLRC1 LMNA MS4A14 NRG1 PEX19 PSCA PVR RBBP8 SERINC2 SLC12A7 SLC39A2 TIMMDC1 TMEM52B TSPO2 UPK1B
Entrez ID		347735	113452
HPRD ID		15481	12524
Ensembl ID		ENSG00000168528	ENSG00000121900
Uniprot IDs		Q96IM8 Q96SA4	Q969K7
PDB IDs
Enriched GO Terms of Interacting Partners?
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