TMEM54 and SLC12A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM54	SLC12A7
Description		transmembrane protein 54	solute carrier family 12 member 7
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Protein-containing Complex Synapse
	Molecular Function	Molecular_function Protein Binding	Ammonium Transmembrane Transporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding
	Biological Process	Biological_process	Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Ammonium Import Across Plasma Membrane Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways			Cation-coupled Chloride cotransporters
Drugs			Potassium chloride
Diseases
GWAS		Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)	Granulocyte count ( 27863252) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte percentage of red cells ( 32888494) JT interval ( 29874175) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010 32888494 20139978 27863252) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Pancreatic cancer ( 25086665) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494) PR interval ( 32439900) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Weight ( 28552196) White blood cell count ( 32888494)
Interacting Genes		25 interacting genes: ARL13B CD3G CLSTN3 CREB3 FKBP7 GPR152 GPR37L1 HPCA KCNJ8 KCNK5 KLRC1 LMNA MS4A14 NRG1 PEX19 PSCA PVR RBBP8 SERINC2 SLC12A7 SLC39A2 TIMMDC1 TMEM52B TSPO2 UPK1B	14 interacting genes: GJB1 GPR61 MS4A13 OPRD1 OTP SERINC2 SLC10A1 SLC10A6 SLC35C2 TMBIM6 TMEM147 TMEM237 TMEM54 YIPF6
Entrez ID		113452	10723
HPRD ID		12524	09221
Ensembl ID		ENSG00000121900	ENSG00000113504
Uniprot IDs		Q969K7	Q9Y666
PDB IDs			7D99
Enriched GO Terms of Interacting Partners?
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