SERINC2 and SEC22B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SERINC2	SEC22B
Description		serine incorporator 2	SEC22 homolog B, vesicle trafficking protein
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Phagocytic Vesicle Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome
	Molecular Function		SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Phosphatidylserine Metabolic Process Sphingolipid Metabolic Process Positive Regulation Of CDP-diacylglycerol-serine O-phosphatidyltransferase Activity Positive Regulation Of Serine C-palmitoyltransferase Activity	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Positive Regulation Of Protein Catabolic Process Vesicle Fusion With Golgi Apparatus Negative Regulation Of Autophagosome Assembly
Pathways		Serine biosynthesis	ER-Phagosome pathway COPII-mediated vesicle transport Cargo concentration in the ER COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heart rate response to recovery post exercise (50 sec) ( 29497042) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Iris color (L* coordinate) ( 30895295)
Interacting Genes		16 interacting genes: C4orf3 CCDC167 GPX8 LAT MFF SEC22B SLC12A7 SLC29A2 SLC39A9 SMAGP TMEM14A TMEM167B TMEM239 TMEM42 TMEM54 TMEM86B	56 interacting genes: ABHD16A AIG1 AQP6 B3GAT3 CD160 CD79A CERS6 CLDN7 CLRN1 CPLX4 CREB3 CREB3L1 DPM3 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCER1G FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPX8 HIBADH HSD17B13 IFNGR2 JAGN1 KIR2DL3 LHFPL1 LHFPL5 LMNA MFF MFSD5 MGST2 MGST3 MMGT1 MRPS18B NDUFAF2 REEP4 RELL2 RHBDD1 SERINC2 SLC35C2 STX1A STX2 STX4 STX5 TLCD4 TM4SF19 TMEM139 TMEM167B TMEM229B TMEM86B
Entrez ID		347735	9554
HPRD ID		15481	04939
Ensembl ID		ENSG00000168528	ENSG00000265808
Uniprot IDs		Q96IM8 Q96SA4	O75396
PDB IDs			2NUP 2NUT 3EGD 3EGX
Enriched GO Terms of Interacting Partners?
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