RNASE10 and SGPL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RNASE10	SGPL1
Description		ribonuclease A family member 10 (inactive)	sphingosine-1-phosphate lyase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Nucleic Acid Binding Ribonuclease Activity Protein Binding	Protein Binding Sphinganine-1-phosphate Aldolase Activity Pyridoxal Phosphate Binding
	Biological Process	Single Fertilization Positive Regulation Of Cell-cell Adhesion Heterotypic Cell-cell Adhesion Regulation Of Fertilization Positive Regulation Of Flagellated Sperm Motility	Luteinization Vasculogenesis Kidney Development Fatty Acid Metabolic Process Ceramide Metabolic Process Spermatogenesis Androgen Metabolic Process Estrogen Metabolic Process Post-embryonic Development Fibroblast Migration Hemopoiesis Sphingolipid Biosynthetic Process Sphingolipid Catabolic Process Leydig Cell Differentiation Regulation Of Multicellular Organism Growth Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis Roof Of Mouth Development Face Morphogenesis Apoptotic Signaling Pathway
Pathways			Sphingolipid de novo biosynthesis
Drugs			Pyridoxal phosphate
Diseases
GWAS		Immune response to measles-mumps-rubella vaccine ( 24811271)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Metabolite levels ( 23823483) Microalbuminuria ( 26631737) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		6 interacting genes: BFSP2 CREB3L1 MRM1 SGPL1 SGTA SGTB	37 interacting genes: ANK3 AQP3 AQP9 BCL2L2 BRICD5 CCL4L2 CLDN19 DDX21 EFNA5 ERG28 FA2H FAM177A1 FXYD3 HMOX2 IFITM3 MARCHF5 MFSD6 MIP MMD2 PAQR5 PLP2 PLPP4 RNASE10 RTP2 SCAMP5 SLC30A3 SRPK2 STATH STING1 STX4 STX8 TMEM176A TMEM242 TMEM97 TRARG1 TSPAN4 UNC50
Entrez ID		338879	8879
HPRD ID		18495	07224
Ensembl ID		ENSG00000182545	ENSG00000166224
Uniprot IDs		Q5GAN6 W0UTC4	O95470
PDB IDs			4Q6R
Enriched GO Terms of Interacting Partners?
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