SGPL1 and CCL4L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SGPL1	CCL4L2
Description		sphingosine-1-phosphate lyase 1	C-C motif chemokine ligand 4 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Sphinganine-1-phosphate Aldolase Activity Pyridoxal Phosphate Binding
	Biological Process	Luteinization Vasculogenesis Kidney Development Fatty Acid Metabolic Process Ceramide Metabolic Process Spermatogenesis Androgen Metabolic Process Estrogen Metabolic Process Post-embryonic Development Fibroblast Migration Hemopoiesis Sphingolipid Biosynthetic Process Sphingolipid Catabolic Process Leydig Cell Differentiation Regulation Of Multicellular Organism Growth Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis Roof Of Mouth Development Face Morphogenesis Apoptotic Signaling Pathway
Pathways		Sphingolipid de novo biosynthesis	G alpha (i) signalling events
Drugs		Pyridoxal phosphate
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Metabolite levels ( 23823483) Microalbuminuria ( 26631737) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Body mass index ( 26426971) Protein quantitative trait loci ( 18464913)
Interacting Genes		37 interacting genes: ANK3 AQP3 AQP9 BCL2L2 BRICD5 CCL4L2 CLDN19 DDX21 EFNA5 ERG28 FA2H FAM177A1 FXYD3 HMOX2 IFITM3 MARCHF5 MFSD6 MIP MMD2 PAQR5 PLP2 PLPP4 RNASE10 RTP2 SCAMP5 SLC30A3 SRPK2 STATH STING1 STX4 STX8 TMEM176A TMEM242 TMEM97 TRARG1 TSPAN4 UNC50	33 interacting genes: AQP6 ARL13B CATSPER4 CERS4 CLRN1 COMT COQ9 CPLX4 CREB3L1 EBP ELOVL4 ERVFRD-1 FAM209A GET1 GPR152 GPR42 ITM2C JAGN1 MFSD14B MFSD5 MRM1 REEP4 RETREG3 SGPL1 SLC10A2 SLC18A1 SLC30A2 SLC7A1 SLC7A14 SSMEM1 TMEM179B TMEM51 VSIR
Entrez ID		8879	9560
HPRD ID		07224	16030
Ensembl ID		ENSG00000166224	ENSG00000276070
Uniprot IDs		O95470	Q8NHW4
PDB IDs		4Q6R
Enriched GO Terms of Interacting Partners?
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