KRTAP21-2 and CLCNKA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRTAP21-2	CLCNKA
Description		keratin associated protein 21-2	chloride voltage-gated channel Ka
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex
	Molecular Function	Protein Binding	Voltage-gated Chloride Channel Activity Identical Protein Binding Metal Ion Binding
	Biological Process		Chloride Transport Excretion Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport
Pathways		Keratinization	Stimuli-sensing channels
Drugs			Niflumic acid Talniflumate
Diseases
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left ventricular ejection fraction ( 33495596 32382064) Left ventricular end-diastolic volume ( 33495596) Left ventricular end-systolic volume ( 33495596) Left ventricular global circumferential strain ( 33495596) Left ventricular global radial strain ( 33495596) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		30 interacting genes: ADAMTSL4 ATXN1L BEX2 CLCNKA DMRTB1 EFEMP1 FAM221A FOXD2 GATA2 KRTAP10-1 KRTAP12-2 KRTAP26-1 LCE1A LCE2A LCE5A MKRN3 NTN4 PLSCR4 POU4F2 PRR13 RNF38 RNF44 SMARCC1 SMN1 SMN2 SNRPC SPAG8 TCF7L2 VENTX ZIC1	22 interacting genes: C7orf31 CYSRT1 IKZF3 KLHL20 KPRP KRT31 KRT34 KRT37 KRT39 KRTAP21-2 KRTAP4-12 KRTAP6-3 LHX3 MBD3L1 PBX4 SLITRK5 SRPK2 TCF12 TCF4 TEPSIN TRIB3 ZNF511
Entrez ID		337978	1187
HPRD ID		11215	03608
Ensembl ID		ENSG00000187026	ENSG00000186510
Uniprot IDs		Q3LI59	P51800
PDB IDs			2PFI
Enriched GO Terms of Interacting Partners?
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