CLCNKA and KRTAP21-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLCNKA	KRTAP21-2
Description		chloride voltage-gated channel Ka	keratin associated protein 21-2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex	Cytosol Intermediate Filament
	Molecular Function	Voltage-gated Chloride Channel Activity Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Chloride Transport Excretion Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport
Pathways		Stimuli-sensing channels	Keratinization
Drugs		Niflumic acid Talniflumate
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left ventricular ejection fraction ( 33495596 32382064) Left ventricular end-diastolic volume ( 33495596) Left ventricular end-systolic volume ( 33495596) Left ventricular global circumferential strain ( 33495596) Left ventricular global radial strain ( 33495596) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		22 interacting genes: C7orf31 CYSRT1 IKZF3 KLHL20 KPRP KRT31 KRT34 KRT37 KRT39 KRTAP21-2 KRTAP4-12 KRTAP6-3 LHX3 MBD3L1 PBX4 SLITRK5 SRPK2 TCF12 TCF4 TEPSIN TRIB3 ZNF511	30 interacting genes: ADAMTSL4 ATXN1L BEX2 CLCNKA DMRTB1 EFEMP1 FAM221A FOXD2 GATA2 KRTAP10-1 KRTAP12-2 KRTAP26-1 LCE1A LCE2A LCE5A MKRN3 NTN4 PLSCR4 POU4F2 PRR13 RNF38 RNF44 SMARCC1 SMN1 SMN2 SNRPC SPAG8 TCF7L2 VENTX ZIC1
Entrez ID		1187	337978
HPRD ID		03608	11215
Ensembl ID		ENSG00000186510	ENSG00000187026
Uniprot IDs		P51800	Q3LI59
PDB IDs		2PFI
Enriched GO Terms of Interacting Partners?
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