KCNIP3 and SRL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNIP3	SRL
Description		potassium voltage-gated channel interacting protein 3	sarcalumenin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Protein-DNA Complex Axon Terminus	Cytoplasm Plasma Membrane Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Transmembrane Transporter Binding	GTP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Intracellular Protein Transport Apoptotic Process Signal Transduction Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport	Endocytosis Endosomal Transport
Pathways		Phase 1 - inactivation of fast Na+ channels
Drugs
Diseases
GWAS		Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) PR interval ( 32439900) QT interval ( 24952745) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		27 interacting genes: ASPH C1QTNF2 CALM2 CASP3 CD177 CDSN CFLAR CLN3 CREB1 CREM CTBP2 GOLGA7 GRK2 GRK6 IGF1R IGLV3-25 IL6ST KHDC4 MAVS PCBD2 PPP3CA PSEN1 PSEN2 SOD3 SRL TARBP2 ZG16	3 interacting genes: KCNIP3 SGTA VSNL1
Entrez ID		30818	6345
HPRD ID		05232	19351
Ensembl ID		ENSG00000115041	ENSG00000185739
Uniprot IDs		A0A024RE22 Q9Y2W7	B3KPP4 Q86TD4
PDB IDs		2E6W
Enriched GO Terms of Interacting Partners?
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