GZMA and GOLGA2

Number of citations of the paper that reports this interaction (PubMedID 19059912)
25

Data Source:
BioGRID (enzymatic study)

		GZMA	GOLGA2
Description		granzyme A	golgin A2
Image
GO Annotations	Cellular Component	Immunological Synapse Extracellular Region Nucleus	Golgi Cis Cisterna Golgi Membrane Spindle Pole Golgi Apparatus Cis-Golgi Network Microtubule COPII-coated ER To Golgi Transport Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitotic Spindle
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Protein Homodimerization Activity	Protein Binding Microtubule Binding Protein Kinase Binding Syntaxin Binding Identical Protein Binding Cadherin Binding Importin-alpha Family Protein Binding
	Biological Process	Apoptotic Process Immune Response Response To Bacterium Cytolysis Negative Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Negative Regulation Of Oxidoreductase Activity Proteolysis Involved In Cellular Protein Catabolic Process Pyroptosis Granzyme-mediated Programmed Cell Death Signaling Pathway Cytotoxic T Cell Pyroptotic Process	Protein Glycosylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule Nucleation Golgi Organization Centrosome Cycle Asymmetric Cell Division Negative Regulation Of Autophagy Protein Transport Negative Regulation Of Protein Binding Spindle Assembly Protein Homotetramerization Positive Regulation Of Protein Glycosylation Golgi Ribbon Formation Golgi Disassembly Meiotic Spindle Assembly Mitotic Spindle Assembly
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 26426971)
Interacting Genes		19 interacting genes: ACTG1 APEX1 GOLGA2 H1-1 H2BC21 HDC HMGB2 HNRNPK HSP90AA1 HSPA4 LMNA LMNB1 NCL NDUFS3 NFIX PCP4 SET XRCC5 XRCC6	473 interacting genes: ABHD17A ABLIM1 ADAP1 AFF4 ALKBH2 ALKBH3 AMOTL2 ANKHD1 ANKRD11 ANKRD36 ANKRD36BP1 ANKS1A APC AQP1 ARFIP2 ARHGAP45 ARHGEF6 ARID5A ARL16 ARL4A ARNT2 ARPC3 ATP5PO ATP6V1C2 ATP6V1D ATP6V1G1 ATXN7 AXIN1 BAHD1 BARD1 BAZ2B BBLN BCAS2 BCL6 BCL6B BMS1P1 BYSL C12orf50 C19orf44 C1orf109 C1orf35 C2CD6 CAB39 CAPN7 CBX8 CBY2 CCAR1 CCDC120 CCDC13 CCDC146 CCDC150 CCDC17 CCDC185 CCDC187 CCDC198 CCDC70 CCDC87 CCDC92 CCHCR1 CCNC CCNH CDC20B CDC37 CDC5L CDC7 CDC73 CDCA7 CDCA7L CDK1 CDK18 CDKL3 CDKN1A CENPP CEP55 CEP57L1 CEP95 CHCHD2 CHCHD3 CIC CINP CKB CLIP3 COG6 CORO1A COX5B CRACR2A CRMP1 CSPP1 CSTF2T CUL5 CWF19L2 CYB5R2 DAXX DCTN4 DCX DDX6 DEUP1 DGCR6 DLG4 DLGAP3 DLGAP5 DLX6-AS1 DMTN DNM2 DOLPP1 DTX2 DVL2 EAF2 EFCAB6 EFHC1 EGR2 EIF3G EIF4A2 ENKD1 ENPP7 EP300 ERCC3 ESCO2 EXOC8 EXOSC5 FAM110A FAM124B FAM126B FAM161A FAM161B FAM184A FAM193B FAM214A FAM214B FAM50B FAM90A1 FANCG FBF1 FBXL18 FBXO28 FIP1L1 FNDC11 FOXC2 FXR1 FXR2 GADD45GIP1 GAS2L2 GAS8 GATA1 GATA2 GATAD2B GCC1 GEM GFAP GGA2 GGN GLE1 GLYCTK GMCL1 GNG5 GNL3L GORASP1 GORASP2 GPANK1 GPKOW GPS2 GRAP2 GRB14 GSE1 GTPBP10 GZMA GZMK HAUS1 HDAC4 HGS HOXB5 HOXB9 HTRA1 HYLS1 IFT20 IFT27 IGFN1 IHO1 IKZF3 IL16 INPP5J IQCE IQUB ISCU ITGB5 ITPKB ITSN2 KANK2 KANSL1 KAT5 KDM1A KIAA1217 KIFC3 KRT1 KRT18 KRT6A KRT6B KRT6C KRT75 L3MBTL2 LASP1 LATS1 LCOR LCP2 LENG1 LGALS3 LHX4 LIMS2 LIN7A LINGO1 LMNB2 LMO1 LMO2 LMO3 LMO4 LYPLA1 LYSMD1 MAB21L2 MAGOH MAGOHB MBD3 MCM10 MCM7 MCRS1 MFAP1 MID2 MISP MNAT1 MORF4L1 MORF4L2 MORN3 MOS MSRB3 MTFR2 MVP MYEF2 NCF2 NDC80 NDE1 NDEL1 NDN NDUFA5 NEBL NECAB2 NEFL NME7 NMRK1 NOS3 NOTCH1 NSMF NTAQ1 NUDT21 NXT2 OAS1 ODAD4 ODF2 ORC1 PACRGL PARD6B PATL1 PCM1 PIAS2 PIBF1 PID1 PIK3R2 PIMREG PIN1 PITX1 PKN1 PKN3 PKP1 PKP2 PKP4 PLAAT5 PLEKHA2 POLDIP3 POLR3C POM121 POU4F3 PPP1R16B PPP1R18 PPP1R32 PPP2CA PQBP1 PRAM1 PRKAA1 PRKAA2 PRKAB2 PRPF18 PRPF3 PRPF31 PSMA1 PSMA4 PTBP2 PTPN11 PTPN21 RAB1A RAB1B RAB2A RAB2B RAB33B RAB39A RAB39B RAB6A RAD18 RAMAC RANBP3 RANBP3L RBL1 RBM17 RBM22 RBM25 RBM39 RBM41 RCL1 RCOR3 RGS8 RHNO1 RHOJ RHPN1 RIBC1 RIN1 RITA1 RNF135 RNF169 RNF213 RNF214 RNF6 RSPH14 RSRC2 RTP5 RUSC2 RXRB SAMD4A SAP30BP SCAF8 SCEL SCNM1 SECISBP2 SELENOV SFI1 SH2D3C SH2D4A SH3GLB2 SH3RF2 SHC3 SHISA6 SLU7 SLX9 SMARCB1 SMARCE1 SMCP SMG9 SNAP47 SNF8 SNRPB SNRPB2 SNRPC SNTA1 SNW1 SNX18 SORBS2 SPATA18 SPATA2 SPATA22 SPG21 SRSF2 SSX2IP STAC STAMBPL1 STK25 STK26 STN1 SUDS3 SUGP2 SUPT5H SYNPO2L SYT17 SYT6 TBC1D22B TBC1D30 TBP TCEA2 TCEANC TCF19 TCL1A TDP2 TEAD4 TEPSIN TEX9 TFAP4 TFIP11 THAP7 THYN1 TLE5 TMED2 TPM1 TPRX1 TPX2 TRAF1 TRAF3IP2 TRAF4 TRAF5 TRIM14 TRIM29 TRIM42 TSC1 TSC22D4 TSGA10 TSGA10IP TSHZ2 TSHZ3 TSSC4 TSSK3 TTC23 TTC9C TTPA TUBGCP4 TXLNA TXLNB UBE2H UBE2I UBE2U UBE3C UBTFL1 USO1 USP15 USP2 UTP14C UTP23 VPS28 VPS37C WASHC3 WHRN WT1 XIAP YJU2 YTHDC1 ZBTB16 ZBTB4 ZBTB42 ZC2HC1C ZER1 ZFC3H1 ZFHX3 ZFP2 ZFYVE26 ZG16B ZGPAT ZMAT1 ZMAT2 ZNF124 ZNF250 ZNF280C ZNF3 ZNF35 ZNF410 ZNF414 ZNF417 ZNF438 ZNF48 ZNF488 ZNF512B ZNF524 ZNF572 ZNF581 ZNF587 ZNF594 ZNF648 ZNF688 ZNF774 ZNF835 ZZZ3
Entrez ID		3001	2801
HPRD ID		00771	03989
Ensembl ID		ENSG00000145649	ENSG00000167110
Uniprot IDs		P12544	Q08379
PDB IDs		1HF1 1OP8 1ORF	4REY 6IW8 6IWA 6K06
Enriched GO Terms of Interacting Partners?
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