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GZMA

Description granzyme A
Image
GO Annotations Cellular Component
  • Immunological Synapse
  • Extracellular Region
  • Nucleus
Molecular Function
  • Serine-type Endopeptidase Activity
  • Protein Binding
  • Protein Homodimerization Activity
Biological Process
  • Apoptotic Process
  • Immune Response
  • Response To Bacterium
  • Cytolysis
  • Negative Regulation Of Endodeoxyribonuclease Activity
  • Positive Regulation Of Apoptotic Process
  • Negative Regulation Of DNA Binding
  • Negative Regulation Of Oxidoreductase Activity
  • Proteolysis Involved In Cellular Protein Catabolic Process
  • Pyroptosis
  • Granzyme-mediated Programmed Cell Death Signaling Pathway
  • Cytotoxic T Cell Pyroptotic Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 19 interacting genes: ACTG1 APEX1 GOLGA2 H1-1 H2BC21 HDC HMGB2 HNRNPK HSP90AA1 HSPA4 LMNA LMNB1 NCL NDUFS3 NFIX PCP4 SET XRCC5 XRCC6
Entrez ID 3001
HPRD ID 00771
Ensembl ID ENSG00000145649
Uniprot IDs P12544
PDB IDs 1HF1 1OP8 1ORF
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025