GUCA1A and BCKDK

		GUCA1A	BCKDK
Description		guanylate cyclase activator 1A	branched chain keto acid dehydrogenase kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Photoreceptor Disc Membrane Cone Photoreceptor Outer Segment	Mitochondrion Mitochondrial Matrix Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex
	Molecular Function	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity Guanylate Cyclase Regulator Activity	Protein Serine/threonine Kinase Activity Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Protein Binding ATP Binding Kinase Activity [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity
	Biological Process	Signal Transduction Visual Perception Phototransduction Positive Regulation Of CGMP-mediated Signaling Positive Regulation Of Guanylate Cyclase Activity Cellular Response To Calcium Ion	Protein Phosphorylation Isoleucine Catabolic Process Leucine Catabolic Process Valine Catabolic Process Spermatogenesis Cellular Amino Acid Catabolic Process Branched-chain Amino Acid Catabolic Process Regulation Of Glucose Metabolic Process Phosphorylation Negative Regulation Of Cellular Amino Acid Metabolic Process
Pathways		Inactivation, recovery and regulation of the phototransduction cascade	Branched-chain amino acid catabolism
Drugs		Myristic acid	Adenosine 5'-[gamma-thio]triphosphate
Diseases
GWAS		Spatial processing ( 31596458)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Parkinson's disease ( 25064009) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498) Waist circumference ( 31928498)
Interacting Genes		10 interacting genes: AGR2 BCKDK C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B	20 interacting genes: APP BCKDHB CDIPT EIF3C EPS8 FBXO7 FOXO1 FXR1 FXR2 GUCA1A LSM8 NR5A2 PCDHB9 QPRT SETD1A SPTA1 STAT3 TAOK2 TRAF4 ZNF267
Entrez ID		2978	10295
HPRD ID		02648	12523
Ensembl ID		ENSG00000048545	ENSG00000103507
Uniprot IDs		B2R9P6 P43080	A0A024QZA9 O14874
PDB IDs
Enriched GO Terms of Interacting Partners?
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