BCKDK and QPRT

		BCKDK	QPRT
Description		branched chain keto acid dehydrogenase kinase	quinolinate phosphoribosyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex	Cytoplasm Cytosol Extracellular Exosome Catalytic Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Protein Binding ATP Binding Kinase Activity [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity	Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity Protein Binding Identical Protein Binding
	Biological Process	Protein Phosphorylation Isoleucine Catabolic Process Leucine Catabolic Process Valine Catabolic Process Spermatogenesis Cellular Amino Acid Catabolic Process Branched-chain Amino Acid Catabolic Process Regulation Of Glucose Metabolic Process Phosphorylation Negative Regulation Of Cellular Amino Acid Metabolic Process	NAD Biosynthetic Process NAD Metabolic Process Quinolinate Catabolic Process
Pathways		Branched-chain amino acid catabolism	Nicotinate metabolism
Drugs		Adenosine 5'-[gamma-thio]triphosphate	Niacin
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Parkinson's disease ( 25064009) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498) Waist circumference ( 31928498)
Interacting Genes		20 interacting genes: APP BCKDHB CDIPT EIF3C EPS8 FBXO7 FOXO1 FXR1 FXR2 GUCA1A LSM8 NR5A2 PCDHB9 QPRT SETD1A SPTA1 STAT3 TAOK2 TRAF4 ZNF267	11 interacting genes: ADAMTSL4 BCKDK ETS1 GIT2 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-8 KRTAP4-12 NOTCH2NLA SUFU
Entrez ID		10295	23475
HPRD ID		12523	06950
Ensembl ID		ENSG00000103507	ENSG00000103485
Uniprot IDs		A0A024QZA9 O14874	B4DDH4 Q15274 V9HWJ5
PDB IDs			2JBM 4KWV 4KWW 5AYX 5AYY 5AYZ
Enriched GO Terms of Interacting Partners?
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