GSTM4 and APLP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GSTM4	APLP1
Description		glutathione S-transferase mu 4	amyloid beta precursor like protein 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Intercellular Bridge	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Protein Binding Enzyme Binding Protein Homodimerization Activity Glutathione Binding	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	Glutathione Metabolic Process Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Long-chain Fatty Acid Biosynthetic Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways		Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Drugs		Glutathione Glutathione sulfonic acid S-octylglutathione Glutathione disulfide gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane S-Hexylglutathione	Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Alcohol dependence ( 33290381) Seasonality and depression ( 30217971)	Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		11 interacting genes: APLP1 GSTM3 GSTM5 IGSF21 LRIF1 MED31 NELFCD TLE1 TP53 UNC119 ZBTB16	43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24
Entrez ID		2948	333
HPRD ID		00706	00102
Ensembl ID		ENSG00000168765	ENSG00000105290
Uniprot IDs		A0A140VKE3 Q03013	P51693
PDB IDs		4GTU	3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA
Enriched GO Terms of Interacting Partners?
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