GSTM4 and NELFCD

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GSTM4	NELFCD
Description		glutathione S-transferase mu 4	negative elongation factor complex member C/D
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Intercellular Bridge	Nucleoplasm Membrane NELF Complex
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Protein Binding Enzyme Binding Protein Homodimerization Activity Glutathione Binding	RNA Binding Protein Binding
	Biological Process	Glutathione Metabolic Process Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Long-chain Fatty Acid Biosynthetic Process	Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Pathways		Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs		Glutathione Glutathione sulfonic acid S-octylglutathione Glutathione disulfide gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane S-Hexylglutathione
Diseases
GWAS		Alcohol dependence ( 33290381) Seasonality and depression ( 30217971)	Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 27863252)
Interacting Genes		11 interacting genes: APLP1 GSTM3 GSTM5 IGSF21 LRIF1 MED31 NELFCD TLE1 TP53 UNC119 ZBTB16	22 interacting genes: AAMP AR ARAF ARPC4 CACNA1A CD40 CDSN DNAJA1 ENDOV EPRS1 FRMD5 GSTM4 HDAC11 MTA1 NELFA OGT PRMT5 SERF2 SMAD4 TXK UBE3A ZNF638
Entrez ID		2948	51497
HPRD ID		00706	16096
Ensembl ID		ENSG00000168765	ENSG00000101158
Uniprot IDs		A0A140VKE3 Q03013	H0UI80 Q8IXH7
PDB IDs		4GTU	5L3X 6GML
Enriched GO Terms of Interacting Partners?
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