APLP1 and CRCT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APLP1	CRCT1
Description		amyloid beta precursor like protein 1	cysteine rich C-terminal 1
Image			No pdb structure
GO Annotations	Cellular Component	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	Protein Binding
	Biological Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Severe influenza A (H1N1) infection ( 26379185)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 21804549 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 26482879) Obesity-related traits ( 23251661) Plantar warts ( 28928442)
Interacting Genes		43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	55 interacting genes: AGTRAP ALPP APLP1 CEP126 CHD3 CYP21A2 CYSRT1 EEF1A1 GRN IGSF21 KRTAP1-3 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1C LCE1F LCE2B LCE2C LCE4A LRIF1 MACO1 MEOX2 NOTCH2NLA NUP62 OIT3 PLSCR4 PTN RGS17 RGS20 SDCBP2 SLC39A7 TGM1 TLE1 TRIM55 TRIM63 VIM VWC2L
Entrez ID		333	54544
HPRD ID		00102	16635
Ensembl ID		ENSG00000105290	ENSG00000169509
Uniprot IDs		P51693	Q9UGL9
PDB IDs		3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA
Enriched GO Terms of Interacting Partners?
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