GRSF1 and MYCN

Number of citations of the paper that reports this interaction (PubMedID 17967896)
69

Data Source:
BioGRID (unspecified method)

		GRSF1	MYCN
Description		G-rich RNA sequence binding factor 1	MYCN proto-oncogene, bHLH transcription factor
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Ribonucleoprotein Granule Mitochondrial Nucleoid Ribonucleoprotein Complex	Chromatin Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Kinase Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Mitochondrial RNA Catabolic Process MRNA Polyadenylation TRNA Processing Anterior/posterior Pattern Specification Morphogenesis Of Embryonic Epithelium Regulation Of RNA Splicing	Cartilage Condensation Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Death Lung Development Embryonic Digit Morphogenesis Regulation Of Inner Ear Auditory Receptor Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Negative Regulation Of Astrocyte Differentiation Branching Morphogenesis Of An Epithelial Tube Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Viral mRNA Translation	Signaling by ALK
Drugs
Diseases
GWAS		Type 2 diabetes ( 30718926)	Asthma or chronic obstructive pulmonary disease ( 24993907) Basal cell carcinoma ( 25855136) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 31562340) Lymphocyte counts ( 32888494) Metabolite levels ( 23823483) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft palate ( 31609978) Pulmonary function (smoking interaction) ( 23284291) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Wilms tumor ( 22544364)
Interacting Genes		27 interacting genes: MIR1-2 MIR106B MIR18B MIR200B MIR200C MIR205 MIR25 MIR31 MIR451A MIR9-1 MIR9-2 MIR92A1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I MYCN OGT PRKN PSMD10	20 interacting genes: CSNK2A1 CSNK2A2 DOT1L EZH2 FBXW7 GRSF1 HUWE1 MAX MXD1 NEDD4 NMI NONO RUNX3 SIRT1 SP1 TRIM32 YAF2 YBX1 YEATS4 ZBTB17
Entrez ID		2926	4613
HPRD ID		07276	01278
Ensembl ID		ENSG00000132463	ENSG00000134323
Uniprot IDs		A0A024RD99 Q12849	A0A1W2PPD9 P04198 Q9H224
PDB IDs		2LMI 4QU6 4QU7	5G1X
Enriched GO Terms of Interacting Partners?
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