BRD7 and PTPN13

Number of citations of the paper that reports this interaction (PubMedID 10526152)
7

Data Source:
HPRD (two hybrid, in vivo)

		BRD7	PTPN13
Description		bromodomain containing 7	protein tyrosine phosphatase non-receptor type 13
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Lamellipodium Neuron Projection Cell Body Extracellular Exosome
	Molecular Function	Transcription Cis-regulatory Region Binding P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Histone Binding Lysine-acetylated Histone Binding	Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Cycle Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Negative Regulation Of Protein Phosphorylation Protein Dephosphorylation Regulation Of Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Dephosphorylation
Pathways		Regulation of TP53 Activity through Acetylation	Synthesis of PIPs at the plasma membrane Interleukin-37 signaling RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Allergic sensitization ( 30013184) Epilepsy ( 30531953) Liver enzyme levels (alanine transaminase) ( 24124411) Medication use (thyroid preparations) ( 31015401)	Eyebrow thickness ( 26926045) Hemoglobin levels ( 32327693) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 27647854) Kidney disease (end stage renal disease vs normoalbuminuria) in type 1 diabetes ( 27647854) Tinnitus ( 33742053) Word spelling ( 30741946)
Interacting Genes		30 interacting genes: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 H2AC16 H2BC21 H3-3A H3-4 H3C14 H4-16 HAP1 HNRNPUL1 IRF2 LAMA4 LRIF1 MX1 NEFL PAFAH1B3 PARP1 PCBD1 PLEKHF2 PSMD11 PTPN13 RIF1 RPLP1 SERPINB9 TRIM24	24 interacting genes: APC ARHGAP29 BEX3 BRD7 CRHR1 CRIP2 CTNNB1 EFNB1 EFNB2 FADD FAS FASLG GHR MTNR1A NFKBIA NGFR PDLIM4 PKN2 PLEKHA1 PLEKHA2 PRKACA RAPGEF6 TRIP6 YWHAZ
Entrez ID		29117	5783
HPRD ID		12531	02602
Ensembl ID		ENSG00000166164	ENSG00000163629
Uniprot IDs		Q9NPI1	Q12923
PDB IDs		2I7K 5MQ1 6PPA 6V0Q 6V16 6V17 6V1E 6V1F 6V1H	1D5G 1Q7X 1WCH 2M0Z 2M10 3LNX 3LNY 3PDZ 5GLJ
Enriched GO Terms of Interacting Partners?
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