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BRD7

Description bromodomain containing 7
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
Molecular Function
  • Transcription Cis-regulatory Region Binding
  • P53 Binding
  • Transcription Coactivator Activity
  • Transcription Corepressor Activity
  • Protein Binding
  • Histone Binding
  • Lysine-acetylated Histone Binding
Biological Process
  • Regulation Of Transcription By RNA Polymerase II
  • Cell Cycle
  • Negative Regulation Of Cell Population Proliferation
  • Wnt Signaling Pathway
  • Positive Regulation Of Histone Acetylation
  • Negative Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Transcription, DNA-templated
  • Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
  • Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS
  • Allergic sensitization ( 30013184)
  • Epilepsy ( 30531953)
  • Liver enzyme levels (alanine transaminase) ( 24124411)
  • Medication use (thyroid preparations) ( 31015401)
Interacting Genes 30 interacting genes: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 H2AC16 H2BC21 H3-3A H3-4 H3C14 H4-16 HAP1 HNRNPUL1 IRF2 LAMA4 LRIF1 MX1 NEFL PAFAH1B3 PARP1 PCBD1 PLEKHF2 PSMD11 PTPN13 RIF1 RPLP1 SERPINB9 TRIM24
Entrez ID 29117
HPRD ID 12531
Ensembl ID ENSG00000166164
Uniprot IDs Q9NPI1
PDB IDs 2I7K 5MQ1 6PPA 6V0Q 6V16 6V17 6V1E 6V1F 6V1H
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025