PTPN13 and PLEKHA2

Number of citations of the paper that reports this interaction (PubMedID 14516276)
12

Data Source:
BioGRID (pull down)

		PTPN13	PLEKHA2
Description		protein tyrosine phosphatase non-receptor type 13	pleckstrin homology domain containing A2
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Lamellipodium Neuron Projection Cell Body Extracellular Exosome	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding	Fibronectin Binding Protein Binding Lipid Binding PDZ Domain Binding Laminin Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Protein Dephosphorylation Regulation Of Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Dephosphorylation	Positive Regulation Of Cell-matrix Adhesion
Pathways		Synthesis of PIPs at the plasma membrane Interleukin-37 signaling RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Hemoglobin levels ( 32327693) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 27647854) Kidney disease (end stage renal disease vs normoalbuminuria) in type 1 diabetes ( 27647854) Tinnitus ( 33742053) Word spelling ( 30741946)	High density lipoprotein cholesterol levels ( 31211820) Monocyte percentage of white cells ( 32888494)
Interacting Genes		24 interacting genes: APC ARHGAP29 BEX3 BRD7 CRHR1 CRIP2 CTNNB1 EFNB1 EFNB2 FADD FAS FASLG GHR MTNR1A NFKBIA NGFR PDLIM4 PKN2 PLEKHA1 PLEKHA2 PRKACA RAPGEF6 TRIP6 YWHAZ	19 interacting genes: COG6 DLG2 DLG3 EGLN3 FHL5 GIPC1 GIPC2 GIPC3 GOLGA2 HSF2BP KANK2 LNX1 M1AP MPDZ PLEKHA1 PTPN13 SNTG1 TEPSIN TRIM23
Entrez ID		5783	59339
HPRD ID		02602
Ensembl ID		ENSG00000163629	ENSG00000169499
Uniprot IDs		Q12923	A0A087WZ32 A8K727 Q9HB19
PDB IDs		1D5G 1Q7X 1WCH 2M0Z 2M10 3LNX 3LNY 3PDZ 5GLJ
Enriched GO Terms of Interacting Partners?
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