Description |
growth factor receptor bound protein 10 |
insulin receptor |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Acute lymphoblastic leukemia (childhood) ( 23512250)
- Area under the curve of insulin levels ( 24699409)
- Birth weight ( 31043758)
- Blood pressure (smoking interaction) ( 25189868)
- Body mass index ( 26426971)
- Body mass index (age <50) ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Brain morphology (MOSTest) ( 32665545)
- Chronotype ( 30696823)
- Corpus callosum mid-anterior volume ( 31530798)
- Corrected insulin response ( 24699409)
- Corrected insulin response adjusted for insulin sensitivity index ( 24699409)
- Diastolic blood pressure ( 30224653)
- Eosinophil counts ( 32888494 27863252)
- Estimated glomerular filtration rate ( 31152163 31015462)
- Fasting blood glucose ( 22581228)
- Fasting blood glucose (BMI interaction) ( 22581228)
- Fasting glucose ( 33402679 34059833)
- Fasting insulin ( 34059833)
- Femoral neck bone mineral density ( 22504420)
- Fractures ( 30158200)
- Heel bone mineral density ( 30598549)
- Hip circumference adjusted for BMI ( 34021172)
- Incremental insulin ( 24699409)
- Insulin levels adjusted for BMI ( 24699409)
- Insulin-related traits (multivariate analysis) ( 32002517)
- Mean corpuscular volume ( 32888494)
- Mean reticulocyte volume ( 32888494)
- Metabolite levels ( 23823483)
- Morning person ( 30696823)
- Ratio of the area under the curve for insulin and the area under the curve for glucose ( 24699409)
- Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
- Schizophrenia (treatment resistant) ( 25223841)
- Subcortical volume (MOSTest) ( 32665545)
- Sum eosinophil basophil counts ( 27863252)
- Systemic sclerosis ( 21779181)
- Total body bone mineral density ( 29304378)
- Waist circumference adjusted for body mass index ( 34021172)
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Interacting Genes |
48 interacting genes:
AANAT
ABL1
AKT1
APP
BAIAP2
BCR
BLK
CHFR
CNOT9
DOK1
EGFR
ELK1
EPHB1
ERBB2
ERBB4
FARS2
FYN
GHR
GIGYF1
GIGYF2
IGF1R
INSR
IRS1
JAK2
KANK2
KDR
KIT
KPNA3
MAP2K1
MAP3K14
MAPK1
MEGF10
NEDD4
NFKBID
NOA1
PDGFRB
PICK1
RAF1
RET
SRC
TEKT4
TEPSIN
TNK1
TRIM55
TRIM63
TXK
ZDHHC17
ZMYND19
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86 interacting genes:
ACP1
ADRB2
AHSG
ARF1
ARHGAP26
CALM1
CALM2
CALM3
CAV1
CAV3
CBL
CCDC88A
CEACAM1
CRK
CRKL
CSK
DOK1
DOK4
DOK5
DUSP18
DUSP19
ENPP1
ERBB2
FABP4
FRS2
GAB1
GRB10
GRB14
GRB7
HRAS
IGF1R
IGF2
INS
INSRR
IRF7
IRS1
IRS2
JAK1
JAK2
KHDRBS1
KRT27
KRT31
MAD2L1
MAPK3
MARCHF1
PIK3R1
PIK3R3
PLCG1
PRKCA
PRKCD
PTK2
PTPN1
PTPN11
PTPN12
PTPN2
PTPN6
PTPRC
PTPRF
PTPRR
RACK1
RAF1
RASA1
SH2B1
SH2B2
SHC1
SMAD2
SNX1
SNX2
SNX4
SNX6
SOCS1
SOCS2
SOCS3
SOCS6
SORBS1
SRC
STAT5A
STAT5B
STUB1
STYX
SYNCRIP
TEAD1
TRIM72
VAV1
VAV3
YWHAB
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Entrez ID |
2887 |
3643 |
HPRD ID |
03312 |
00975 |
Ensembl ID |
ENSG00000106070
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ENSG00000171105
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Uniprot IDs |
Q13322
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P06213
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PDB IDs |
1NRV
3HK0
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1GAG
1I44
1IR3
1IRK
1P14
1RQQ
2AUH
2B4S
2HR7
2MFR
2Z8C
3BU3
3BU5
3BU6
3EKK
3EKN
3ETA
3W11
3W12
3W13
4IBM
4OGA
4XLV
4XSS
4XST
4ZXB
5E1S
5HHW
5J3H
5KQV
5U1M
6HN4
6HN5
6PXV
6PXW
6SOF
6VEP
6VEQ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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