Description |
insulin receptor |
vav guanine nucleotide exchange factor 3 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
- Asthma and hay fever ( 24388013)
- Autoimmune thyroid disease ( 32581359)
- Bipolar disorder ( 31043756)
- Differentiated thyroid cancer ( 28703219)
- Eosinophil percentage of white cells ( 32888494)
- Facial wrinkles (principal components analysis) ( 33959940)
- Hashimoto thyroiditis versus Graves' disease ( 25429627)
- Hip circumference adjusted for BMI ( 28552196)
- Hypothyroidism ( 30367059 27182965 22493691)
- IgA nephropathy ( 25305756)
- Medication use (thyroid preparations) ( 31015401)
- Night sleep phenotypes ( 27126917)
- Papillary thyroid cancer ( 28703219)
- Plasma thyroid-stimulating hormone levels ( 24722205)
- Refractive error ( 32231278)
- Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
- Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
- Thyroid stimulating hormone levels ( 32769997)
- Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)
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Interacting Genes |
86 interacting genes:
ACP1
ADRB2
AHSG
ARF1
ARHGAP26
CALM1
CALM2
CALM3
CAV1
CAV3
CBL
CCDC88A
CEACAM1
CRK
CRKL
CSK
DOK1
DOK4
DOK5
DUSP18
DUSP19
ENPP1
ERBB2
FABP4
FRS2
GAB1
GRB10
GRB14
GRB7
HRAS
IGF1R
IGF2
INS
INSRR
IRF7
IRS1
IRS2
JAK1
JAK2
KHDRBS1
KRT27
KRT31
MAD2L1
MAPK3
MARCHF1
PIK3R1
PIK3R3
PLCG1
PRKCA
PRKCD
PTK2
PTPN1
PTPN11
PTPN12
PTPN2
PTPN6
PTPRC
PTPRF
PTPRR
RACK1
RAF1
RASA1
SH2B1
SH2B2
SHC1
SMAD2
SNX1
SNX2
SNX4
SNX6
SOCS1
SOCS2
SOCS3
SOCS6
SORBS1
SRC
STAT5A
STAT5B
STUB1
STYX
SYNCRIP
TEAD1
TRIM72
VAV1
VAV3
YWHAB
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25 interacting genes:
AR
CBLB
EGFR
ERBB2
ERBB3
ERBB4
ESR1
GAB1
GRB2
IGF1R
INSR
KIT
LCP2
MET
PIK3R1
PLCG1
RAC1
RHOA
RHOG
RINT1
ROS1
SH3BP2
SHC1
ZRANB1
ZYX
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Entrez ID |
3643 |
10451 |
HPRD ID |
00975 |
05706 |
Ensembl ID |
ENSG00000171105
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ENSG00000134215
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Uniprot IDs |
P06213
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Q9UKW4
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PDB IDs |
1GAG
1I44
1IR3
1IRK
1P14
1RQQ
2AUH
2B4S
2HR7
2MFR
2Z8C
3BU3
3BU5
3BU6
3EKK
3EKN
3ETA
3W11
3W12
3W13
4IBM
4OGA
4XLV
4XSS
4XST
4ZXB
5E1S
5HHW
5J3H
5KQV
5U1M
6HN4
6HN5
6PXV
6PXW
6SOF
6VEP
6VEQ
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2D86
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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