GPS1 and COPS3

Number of citations of the paper that reports this interaction (PubMedID 11337588)
246

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid)

		GPS1	COPS3
Description		G protein pathway suppressor 1	COP9 signalosome subunit 3
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome
	Molecular Function	GTPase Inhibitor Activity Protein Binding	Protein Binding
	Biological Process	Protein Deneddylation JNK Cascade Negative Regulation Of Catalytic Activity	Protein Deneddylation In Utero Embryonic Development Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation RHOBTB1 GTPase cycle	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Reticulocyte count ( 32888494)
Interacting Genes		30 interacting genes: CNOT2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL5 DDB1 ELOB IP6K1 ITPK1 OGT RBX1 SAP130 SENP8 SHANK3 SKP1 SKP2 TBC1D17 TP53 TRIM55 TRIM63 VHL	32 interacting genes: ARAF ARF4 C17orf75 CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CSNK2A1 CSNK2B CUL5 FLAD1 FRS3 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 KRT80 LRP2BP MCPH1 MLF1 NABP1 PRXL2B RAF1 SOS1 TP53
Entrez ID		2873	8533
HPRD ID		15991	07262
Ensembl ID		ENSG00000169727	ENSG00000141030
Uniprot IDs		A0A096LP07 A0A096LPJ3 C9JFE4 Q13098	B4DN01 Q9UNS2
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N	4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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