COPS3 and COPS4

Number of citations of the paper that reports this interaction (PubMedID 11337588)
246

Data Source:
HPRD (in vivo, in vitro)

		COPS3	COPS4
Description		COP9 signalosome subunit 3	COP9 signalosome subunit 4
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome	Nucleus Nucleoplasm Cytosol Synaptic Vesicle COP9 Signalosome Nuclear Speck Cell Junction
	Molecular Function	Protein Binding	Protein Binding NEDD8-specific Protease Activity
	Biological Process	Protein Deneddylation In Utero Embryonic Development Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus	Protein Deneddylation
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Reticulocyte count ( 32888494)	Metabolite levels ( 23823483)
Interacting Genes		32 interacting genes: ARAF ARF4 C17orf75 CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CSNK2A1 CSNK2B CUL5 FLAD1 FRS3 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 KRT80 LRP2BP MCPH1 MLF1 NABP1 PRXL2B RAF1 SOS1 TP53	24 interacting genes: BRME1 CCDC85B COPS2 COPS3 COPS5 COPS6 COPS7A COPS7B COPS8 CUL5 FOS GPS1 IKBKB IL1RN KRT19 MBIP PCDHB12 PEX14 RBX1 RCBTB2 TP53 UBQLN1 USHBP1 YWHAQ
Entrez ID		8533	51138
HPRD ID		07262	09888
Ensembl ID		ENSG00000141030	ENSG00000138663
Uniprot IDs		B4DN01 Q9UNS2	A0A0S2Z5H7 B3KM48 D6RAX7 Q9BT78
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N	4D0P 4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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