KCTD1 and UBASH3A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCTD1	UBASH3A
Description		potassium channel tetramerization domain containing 1	ubiquitin associated and SH3 domain containing A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Centriolar Satellite Intercellular Bridge	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Extracellular Exosome
	Molecular Function	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization	Regulation Of Cytokine Production Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways		Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31015462) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Sudden cardiac arrest ( 21658281)	Addison's disease ( 33574239) Asthma ( 32296059) Autoimmune traits (pleiotropy) ( 30572963) Celiac disease ( 22057235 30572963) Celiac disease and Rheumatoid arthritis ( 26546613) Celiac disease or Rheumatoid arthritis ( 21383967) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Diverticular disease ( 30177863) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Medication use (thyroid preparations) ( 31015401) Primary sclerosing cholangitis ( 27992413) Rheumatoid arthritis ( 30423114 24390342 20453842) Rheumatoid arthritis (ACPA-positive) ( 24532676) Type 1 diabetes ( 21829393 25751624 19430480 30572963 18840781) Vitiligo ( 20410501 27723757)
Interacting Genes		20 interacting genes: EPM2AIP1 EXOSC1 FXR1 KCTD15 LMO1 LMO3 LNX1 MORF4L2 NTAQ1 PICK1 POLR1C PRKAA2 PSMA1 SDCBP TGM7 TRAPPC2 TRAPPC2B UBASH3A UBE2I ZBTB25	92 interacting genes: ARRDC1 ARRDC3 BACE2 BCAR3 C9orf24 CBLB CBS CCDC33 CD3E COPS9 DAZAP2 DDIT4L DISC1 DLGAP4 DNM2 DTX3 FADS6 FAM83A FGFR1OP2 GFAP GOLGA6L9 HSP90AA1 HSP90B1 HSPD1 IKBKG ISY1-RAB43 KCNE1 KCTD1 KIAA0408 KPRP KRT14 KRT31 KRT32 KRT35 KRT39 KRT40 LCN2 LNX1 LZTS1 LZTS2 MAP3K7 MKRN1 N4BP3 NSMF PLEKHB2 PMEPA1 PNMA5 PRDM6 PRKN PSMC1 PSMC4 REL RNF216 RNF41 SF3B4 SH3RF1 SHISA6 SLA2 SLC37A1 SNRNP48 SOS1 SPRY1 SPRY2 STX11 TAX1BP1 TEKT1 TEKT4 TIMM44 TMCO2 TMEM239 TP53BP2 TP63 TRIM27 TRIM37 TRIM5 TRIM50 TRIM8 TUBB8 TYR UBB UBC UBE2L3 VCP VPS37B WAS WASL WBP11 ZBTB42 ZC2HC1C ZNF219 ZNF474 ZRANB1
Entrez ID		284252	53347
HPRD ID		11059	06904
Ensembl ID		ENSG00000134504	ENSG00000160185
Uniprot IDs		A0A024RC45 A0A2U3U043 Q719H9	P57075
PDB IDs		5BXB 5BXD 6S4L	2CRN 5WDI
Enriched GO Terms of Interacting Partners?
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