LSM1 and N4BP1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		LSM1	N4BP1
Description		LSM1 homolog, mRNA degradation associated	NEDD4 binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex	Nucleus Nucleolus Cytosol PML Body
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	MRNA Binding Ribonuclease Activity Protein Binding Ubiquitin Binding
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	Negative Regulation Of Cytokine Production Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of Innate Immune Response RNA Phosphodiester Bond Hydrolysis
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)	Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Serum metabolite levels ( 33031748) Social autistic-like traits ( 24133439) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		34 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 NSD3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11	7 interacting genes: AZI2 CDK6 ITCH LITAF LSM1 MID1 NEDD8
Entrez ID		27257	9683
HPRD ID		06281
Ensembl ID		ENSG00000175324	ENSG00000102921
Uniprot IDs		A0A0S2Z590 O15116	O75113
PDB IDs			6Q3V
Enriched GO Terms of Interacting Partners?
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