LSM1 and DAPL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LSM1	DAPL1
Description		LSM1 homolog, mRNA degradation associated	death associated protein like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	Protein Binding Death Domain Binding
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	Negative Regulation Of Autophagy Cell Differentiation Cellular Response To Amino Acid Starvation Apoptotic Signaling Pathway
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)	Alzheimer's disease in APOE e4+ carriers ( 25778476) LDL cholesterol levels x long total sleep time interaction (1df test) ( 31719535) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Obesity-related traits ( 23251661)
Interacting Genes		34 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 NSD3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11	7 interacting genes: FHL2 FNDC3B LSM1 TRIM55 TRIM63 TSR2 ZIC1
Entrez ID		27257	92196
HPRD ID		06281	18709
Ensembl ID		ENSG00000175324	ENSG00000163331
Uniprot IDs		A0A0S2Z590 O15116	A0PJW8 M1E9T5
PDB IDs
Enriched GO Terms of Interacting Partners?
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