LSM1 and GRHPR

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		LSM1	GRHPR
Description		LSM1 homolog, mRNA degradation associated	glyoxylate and hydroxypyruvate reductase
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex	Cytoplasm Peroxisomal Matrix Cytosol Extracellular Exosome Catalytic Complex
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	Protein Binding Glycerate Dehydrogenase Activity Hydroxypyruvate Reductase Activity Glyoxylate Reductase (NADP+) Activity Carboxylic Acid Binding Protein Homodimerization Activity NAD Binding NADPH Binding
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	Excretion Carboxylic Acid Metabolic Process Dicarboxylic Acid Metabolic Process Glyoxylate Metabolic Process
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease	Glyoxylate metabolism and glycine degradation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)	Bipolar disorder ( 31043756) C-reactive protein levels ( 33339817) Chronotype ( 30696823) Morning person ( 30696823) Severe bacterial meningitis ( 31092817)
Interacting Genes		34 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 NSD3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11	6 interacting genes: CDC7 FOS GLS2 LIG4 LSM1 PTH2R
Entrez ID		27257	9380
HPRD ID		06281	05052
Ensembl ID		ENSG00000175324	ENSG00000137106
Uniprot IDs		A0A0S2Z590 O15116	A0A384N605 Q9UBQ7
PDB IDs			2GCG 2H1S 2Q50 2WWR
Enriched GO Terms of Interacting Partners?
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