PTPN18 and ARHGAP5

Number of citations of the paper that reports this interaction (PubMedID 15588985)
74

Data Source:
HPRD (in vivo)

		PTPN18	ARHGAP5
Description		protein tyrosine phosphatase non-receptor type 18	Rho GTPase activating protein 5
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding SH2 Domain Binding
	Biological Process	Blastocyst Formation Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of ERBB Signaling Pathway	Cell Adhesion Rho Protein Signal Transduction Mammary Gland Development Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Downregulation of ERBB2 signaling Interleukin-37 signaling	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS			Asthma ( 29273806)
Interacting Genes		12 interacting genes: AATK ABL1 ARHGAP5 CDK2 CSK EGFR ERBB2 GAB1 PSTPIP1 PSTPIP2 SRC TEC	12 interacting genes: ADRB2 ITGA5 ITGB1 PTK2B PTPN18 RASA1 RHOA RND1 RND2 RND3 SMURF2 SUZ12
Entrez ID		26469	394
HPRD ID		05961	04060
Ensembl ID		ENSG00000072135	ENSG00000100852
Uniprot IDs		Q99952	Q13017
PDB IDs		2OC3 4GFU 4GFV 4NND	2EE4 2EE5 5U4V
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?