BTBD2 and TDP2

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		BTBD2	TDP2
Description		BTB domain containing 2	tyrosyl-DNA phosphodiesterase 2
Image
GO Annotations	Cellular Component	P-body Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Aggresome Nuclear Body PML Body
	Molecular Function	Protein Binding	Magnesium Ion Binding Single-stranded DNA Binding Transcription Corepressor Activity Nuclease Activity Protein Binding Manganese Ion Binding Tyrosyl-RNA Phosphodiesterase Activity 5'-tyrosyl-DNA Phosphodiesterase Activity
	Biological Process	Neurogenesis	Double-strand Break Repair Cell Surface Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated Neuron Development Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways			Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Mitochondrial DNA copy number (white blood cells) ( 30704525) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)	Colorectal or endometrial cancer ( 26621817)
Interacting Genes		37 interacting genes: BRD7 CCDC90B CCNC CDK2 CINP COPS6 CRMP1 CUL3 DPPA4 EEF1A1 ERG28 FXR1 GAPDH GBP2 GDF9 IGSF21 KPNA2 MLH1 NGB NTAQ1 OSGIN1 PSMD5 PTN RBM48 SETDB1 SMAD1 SMAD2 TDP2 TGFBR1 TLE1 TOP1 TP53 TRIM5 UBR1 UNC119 ZNF512B ZYG11B	37 interacting genes: AKAP9 ATP5MC2 ATXN1 BLK BTBD2 C2orf88 CD40 DLX3 DVL2 EPS8 ETS1 ETS2 FLI1 GOLGA2 JAM2 MAPK6 NOTCH4 PSEN1 RAB11A SKIL SMAD3 SNX13 SRPK2 SUMO1 SUMO2 SUMO3 TAP1 TFIP11 TNFRSF1B TNFRSF8 TRAF2 TRAF3 TRAF5 TRAF6 UBE2I WBP2 ZBED1
Entrez ID		55643	51567
HPRD ID		12252	05771
Ensembl ID		ENSG00000133243	ENSG00000111802
Uniprot IDs		Q9BX70	A0A384MDM5 O95551
PDB IDs		3NO8	5INO 5J3P 5J3S 6Q00 6Q01
Enriched GO Terms of Interacting Partners?
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