APPL1 and RAB5A

  • Number of citations of the paper that reports this interaction (PubMedID 16622416)
  • 228
  • Data Source:
  • BioGRID (proximity labelling technology, two hybrid, proximity labelling technology, affinity chromatography technology, pull down)
  • HPRD (in vivo, in vitro)

APPL1

RAB5A

Description adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 RAB5A, member RAS oncogene family
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 65 interacting genes: ADI1 ADIPOR1 ADIPOR2 AGL AKT1 AKT2 ANKRD1 APPL2 ATP2A1 BATF3 BIN1 BRWD1 C1QTNF9 CBL CBLB CIPC CMTM4 CTTNBP2 DACT1 DCC DNM2 DOK2 DOK3 DOK7 DPYSL5 DTNA DYSF EGFR FARS2 FSHR GPC3 HDAC2 HSPB1 ID1 IMPDH2 INO80E KLF15 KXD1 LUC7L MAGEA9 MAGEC3 MAP3K1 MEOX1 MTA2 MYCBP2 MYH3 PIK3CA PIK3R1 PIK3R2 PLEKHF2 PNMA5 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 SCAPER SH2D2A SOCS6 SPART TP53 TP53BP2 TRAF2 UBE2O ZNF829 35 interacting genes: AGTR1 ALS2CL ANKFY1 APPL1 APPL2 CHML EEA1 GDI2 GRIK4 HTATIP2 ITSN1 NME2 OCRL RAB37 RABAC1 RABEP1 RABEP2 RABGGTB RASA1 RBSN RIN1 RIN2 RIN3 RIT2 RUFY1 SDCBP SGSM3 STX4 TBC1D15 TBC1D17 TBC1D3C TBC1D3F TRIM14 TSC2 USP6NL
Entrez ID 26060 5868
HPRD ID 05053 01542
Ensembl ID ENSG00000157500 ENSG00000144566
Uniprot IDs Q9UKG1 A0A024R2K1 P20339
PDB IDs 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O 5C5B 1N6H 1N6I 1N6K 1N6L 1N6N 1N6O 1N6P 1N6R 1R2Q 1TU3 1TU4 3MJH 4Q9U 7BL1
Enriched GO Terms of Interacting Partners?
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