KANK2 and CCDC88B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KANK2	CCDC88B
Description		KN motif and ankyrin repeat domains 2	coiled-coil domain containing 88B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Membrane
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Dynein Light Intermediate Chain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Negative Regulation Of Cell Population Proliferation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Rho Protein Signal Transduction Negative Regulation Of Programmed Cell Death Negative Regulation Of Vitamin D Receptor Signaling Pathway Kidney Epithelium Development Glomerular Visceral Epithelial Cell Migration Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Positive Regulation Of Cytokine Production Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Positive Regulation Of T Cell Proliferation Defense Response To Protozoan Positive Regulation Of T Cell Activation
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Cholesterol, total ( 26780889) Coronary artery disease ( 29212778) HDL cholesterol ( 23505323) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 31959993) Low density lipoprotein cholesterol levels ( 32902719 32154731) Mean spheric corpuscular volume ( 32888494) NHDL cholesterol levels ( 32902719) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Triglyceride levels ( 32203549)	Basal cell carcinoma ( 31174203 33549134) Crohn's disease ( 28067908) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Inflammatory bowel disease ( 23128233) Keratinocyte cancer (MTAG) ( 31174203) Leprosy ( 25642632) Medication use (thyroid preparations) ( 31015401) Primary biliary cholangitis ( 26394269) Primary sclerosing cholangitis ( 27992413) Sarcoidosis ( 22837380) Triglyceride levels ( 32154731) Type 1 diabetes ( 34127860) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		185 interacting genes: ABI3 AEN ANKRD11 AP2B1 ARL14EP ASB15 BEND7 BIRC7 BLZF1 BORCS6 C11orf1 C2orf68 CADPS CAMK2G CAPN3 CARD10 CARD9 CBX8 CCDC33 CCDC57 CCDC88B CDC20B CDC5L CDKL3 CEACAM6 CEP55 CEP63 CEP70 CHCHD3 CHIC2 CINP COG6 CRX CSNK2A1 CUTC CWF19L2 CYTH4 DDIT4L DLGAP3 DPEP2NB DTX2 DYNLL1 DYNLL2 EFHC2 EIF4E ELOA EXOSC8 FAM161A FAM90A1 FHL2 FHL3 FKBP6 GADD45GIP1 GATA1 GEMIN4 GKAP1 GMCL1 GMNN GOLGA2 GOLGA6A GOLGA6L9 GPANK1 GPKOW GPSM1 GRB10 HAND2 HOMER3 HSF2BP HSPB2 HSPB2-C11orf52 IHO1 IKZF3 IL16 KIF9 KIFAP3 KIFC3 KRT27 KRT34 KRT40 KRT75 KRT86 KRTAP6-3 L3MBTL3 LBX1 LENG1 LHX1 LHX3 LMO1 LMO2 LMO3 LMO4 LZTS1 MAGEB4 MCCD1 MCRS1 MED19 MEOX1 MEOX2 MID2 MITD1 MKRN3 MOB1A MOB3C MORN3 MSS51 MTUS2 MYOZ3 NCOA1 NCOA5 NECAB2 NOS3 NUTM1 OIP5 PAX6 PCBD1 PDE9A PDLIM7 PFDN6 PIBF1 PLAGL2 PLEKHA2 PNKP PPP1CB PRDM14 PRDM6 PRKAR1B PRMT5 PRPF18 PRPF31 PRR5L PSEN1 PSMB4 PSTPIP1 RAB11FIP2 RALBP1 RBCK1 RHOH SCARA5 SCNM1 SERTAD3 SNAPIN SNW1 SORBS3 SRPK2 STAC SYT6 TAX1BP1 TEX11 TFIP11 TGM5 THAP1 THAP6 TIFA TLE5 TOP3B TRAF1 TRAF2 TRAF4 TRIB3 TRIM35 TRIM54 TSGA10 TSGA10IP TSPYL6 TXLNA UBAP2 USHBP1 UTP14C VMAC VPS52 VWC2 WASF3 WASHC1 ZBTB42 ZFP57 ZMAT2 ZMYND12 ZNF212 ZNF414 ZNF512 ZNF648 ZNF774 ZNF784 ZNHIT1 ZRANB1	41 interacting genes: BEX2 C1orf109 CARD9 CCHCR1 CDK18 CWF19L2 DEF6 DTNB EXOSC5 FAM161A FAM161B GEM HCK HOXB5 JAKMIP2 KANK2 LMNB1 LMNB2 LMO1 LNX1 NME7 PBX2 PIN1 PLEKHA5 PPP1R18 RALBP1 RBM7 RINT1 SH2D4A SH3KBP1 SRPK2 TBC1D22B TRAF3IP3 TSC1 TSG101 TSGA10 TSGA10IP TSHZ2 TXLNB USP2 ZC2HC1C
Entrez ID		25959	283234
HPRD ID		12463	10986
Ensembl ID		ENSG00000197256	ENSG00000168071
Uniprot IDs		Q63ZY3	A6NC98 B2RTU8
PDB IDs		4HBD 5YBV 6TMD
Enriched GO Terms of Interacting Partners?
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