CCDC88B and TSHZ2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC88B	TSHZ2
Description		coiled-coil domain containing 88B	teashirt zinc finger homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Membrane	Chromatin Nucleus
	Molecular Function	Protein Binding Microtubule Binding Dynein Light Intermediate Chain Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Cytokine Production Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Positive Regulation Of T Cell Proliferation Defense Response To Protozoan Positive Regulation Of T Cell Activation	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203 33549134) Crohn's disease ( 28067908) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Inflammatory bowel disease ( 23128233) Keratinocyte cancer (MTAG) ( 31174203) Leprosy ( 25642632) Medication use (thyroid preparations) ( 31015401) Primary biliary cholangitis ( 26394269) Primary sclerosing cholangitis ( 27992413) Sarcoidosis ( 22837380) Triglyceride levels ( 32154731) Type 1 diabetes ( 34127860) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Alcohol consumption (max-drinks) ( 29460428) Apolipoprotein A1 levels ( 32203549) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Body shape index ( 34021172) Coronary artery aneurysm in Kawasaki disease ( 27171184) Crohn's disease ( 32581322) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) Hemoglobin ( 19862010) Hip index ( 34021172) Parkinson's disease ( 26227905) Spatial memory ( 31596458) Triglyceride levels ( 32203549) Triglyceride levels x loop diuretics use interaction ( 31806883) Type 2 diabetes ( 30297969) Type 2 diabetes (age of onset) ( 28060188) Urinary metabolite levels in chronic kidney disease ( 29545352) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		41 interacting genes: BEX2 C1orf109 CARD9 CCHCR1 CDK18 CWF19L2 DEF6 DTNB EXOSC5 FAM161A FAM161B GEM HCK HOXB5 JAKMIP2 KANK2 LMNB1 LMNB2 LMO1 LNX1 NME7 PBX2 PIN1 PLEKHA5 PPP1R18 RALBP1 RBM7 RINT1 SH2D4A SH3KBP1 SRPK2 TBC1D22B TRAF3IP3 TSC1 TSG101 TSGA10 TSGA10IP TSHZ2 TXLNB USP2 ZC2HC1C	21 interacting genes: APBB1 BACH2 CCDC57 CCDC88B CNTROB COG3 CRACR2B GIGYF1 GOLGA2 GRIPAP1 MCC PHAF1 PIBF1 PNMA1 RABEP1 RINT1 SPTA1 TFIP11 TRAF1 TRAF2 UBE2I
Entrez ID		283234	128553
HPRD ID		10986	10730
Ensembl ID		ENSG00000168071	ENSG00000182463
Uniprot IDs		A6NC98 B2RTU8	Q9NRE2
PDB IDs
Enriched GO Terms of Interacting Partners?
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