MOB4 and PAICS

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MOB4	PAICS
Description		MOB family member 4, phocein	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Golgi Cisterna Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding
	Biological Process		'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process
Pathways			Purine ribonucleoside monophosphate biosynthesis
Drugs			Aspartic acid
Diseases
GWAS		Allergic rhinitis ( 31361310) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Schizophrenia ( 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		33 interacting genes: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 HSPD1 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PPIL3 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2	21 interacting genes: CDC37 CEP76 CHD3 FXR1 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PIAS2 PILRA PRKAG1 PTPRC RAD54L2 RNF4 SMARCD1 TERF1 UBE2I UBE3A ZMYM2
Entrez ID		25843	10606
HPRD ID		10165	01401
Ensembl ID		ENSG00000115540	ENSG00000128050
Uniprot IDs		A0A024R3X9 Q9Y3A3	P22234
PDB IDs		5YF4	2H31 6YB8 6YB9
Enriched GO Terms of Interacting Partners?
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