MOB4 and MYO9B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		MOB4	MYO9B
Description		MOB family member 4, phocein	myosin IXB
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Golgi Cisterna Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Actin Filament Cell Cortex Actin Cytoskeleton Membrane Myosin Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Metal Ion Binding	Microfilament Motor Activity Actin Binding GTPase Activator Activity Protein Binding Calmodulin Binding ATP Binding Small GTPase Binding Protein Homodimerization Activity ADP Binding Metal Ion Binding Roundabout Binding
	Biological Process		Rho Protein Signal Transduction Actin Filament-based Movement ARF Protein Signal Transduction Regulation Of Rho Protein Signal Transduction Roundabout Signaling Pathway Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Regulation of actin dynamics for phagocytic cup formation RHOA GTPase cycle SLIT2:ROBO1 increases RHOA activity RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOF GTPase cycle FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Allergic rhinitis ( 31361310) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Schizophrenia ( 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Asthma ( 32296059) Body shape index ( 34021172) Coronary artery disease ( 29212778 33020668) Diastolic blood pressure ( 27841878) Glycated hemoglobin levels ( 24647736 34059833 28898252) Height ( 20881960 31562340 29782485) hemolysis of donated blood (osmotic) ( 34014839) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Night sleep phenotypes ( 27126917) Platelet count ( 29403010 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Prostate cancer ( 29892016) Prostate cancer (early onset) ( 29892016) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Selective IgA deficiency ( 27723758) Spleen volume ( 34128465) Systolic blood pressure ( 27841878 30578418) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 28552196 34021172)
Interacting Genes		33 interacting genes: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 HSPD1 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PPIL3 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2	7 interacting genes: ACTA1 ARFGEF1 CALM1 LRRC41 MOB4 PKN2 RAB8A
Entrez ID		25843	4650
HPRD ID		10165	03677
Ensembl ID		ENSG00000115540	ENSG00000099331
Uniprot IDs		A0A024R3X9 Q9Y3A3	B0I1T6 Q13459 Q4LE74 Q8WVD2
PDB IDs		5YF4	5C5S 5HPY
Enriched GO Terms of Interacting Partners?
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