GAD2 and MRM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GAD2	MRM3
Description		glutamate decarboxylase 2	mitochondrial rRNA methyltransferase 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Axon Synaptic Vesicle Membrane Anchored Component Of Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane	Mitochondrion Mitochondrial Matrix
	Molecular Function	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding	RNA Binding Protein Binding Identical Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity
	Biological Process	Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Response To Xenobiotic Stimulus Neurotransmitter Biosynthetic Process	RRNA 2'-O-methylation
Pathways		GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling	rRNA modification in the mitochondrion
Drugs		Pyridoxal phosphate Glutamic acid
Diseases
GWAS		Fasting glucose ( 34059833) Glycated hemoglobin levels ( 34059833) Lean body mass ( 28552196)
Interacting Genes		48 interacting genes: ABHD5 AGTRAP APOC2 APOC4 ARL13B ARL6IP1 ARMC12 BASP1 BSND CACNG1 CALM1 CMTM5 CPLX4 CYB561D1 DERL1 DERL3 DGAT2L6 DMKN F10 FADS6 FAM114A2 FAM163A GAD1 HIGD1C LDAF1 LIME1 MAL2 MAP3K8 MEST MRM3 PBX3 PLIN3 PRKACA PRKCE RDH10 RHEX RPRM SCAMP1 SDR16C5 SEC22A SMPD2 SPG21 SYCE2 SYNGR3 TMEM120B TMEM128 TNFRSF10D TSPAN33	16 interacting genes: AIG1 APP BTN2A2 C4orf3 FBXO7 FHL3 GAD2 GALNT2 JAGN1 MIP OGT SCARF1 SHANK3 TNF UBIAD1 ZFPL1
Entrez ID		2572	55178
HPRD ID		11817	15266
Ensembl ID		ENSG00000136750	ENSG00000171861
Uniprot IDs		Q05329 Q5VZ30	Q9HC36
PDB IDs		1ES0 2OKK
Enriched GO Terms of Interacting Partners?
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