MRM3 and GALNT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MRM3	GALNT2
Description		mitochondrial rRNA methyltransferase 3	polypeptide N-acetylgalactosaminyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Golgi Membrane Extracellular Region Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Membrane Integral Component Of Golgi Membrane Golgi Cisterna Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity	Polypeptide N-acetylgalactosaminyltransferase Activity Protein Binding Manganese Ion Binding Carbohydrate Binding
	Biological Process	RRNA 2'-O-methylation	Protein O-linked Glycosylation O-glycan Processing Protein O-linked Glycosylation Via Serine Protein O-linked Glycosylation Via Threonine Protein Maturation
Pathways		rRNA modification in the mitochondrion	COPI-independent Golgi-to-ER retrograde traffic O-linked glycosylation of mucins
Drugs
Diseases
GWAS			Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Blood protein levels ( 29875488) Carotid intima media thickness ( 26343869) Circulating myeloperoxidase levels (serum) ( 23620142) Coronary artery disease ( 29212778) Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Fibrinogen levels ( 28107422) HDL cholesterol ( 24097068 18193043 18193044 20864672 19060906 30275531 25961943 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Hematology traits ( 23303382) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High density lipoprotein cholesterol levels ( 29403010 33339817) Intake of sweets ( 31005972) Mean corpuscular hemoglobin concentration ( 32888494) Mean platelet volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 22399527 31589552) Metabolite levels ( 22916037) Metabolite levels (lipoprotein measures) ( 27005778) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Postburn scar pliability ( 30595539) Red cell distribution width ( 32888494 27863252 28957414) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 32203549 28334899 32902719 32154731 29403010 33339817 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068 18193043 18193044 30275531 25961943 20686565)
Interacting Genes		16 interacting genes: AIG1 APP BTN2A2 C4orf3 FBXO7 FHL3 GAD2 GALNT2 JAGN1 MIP OGT SCARF1 SHANK3 TNF UBIAD1 ZFPL1	7 interacting genes: BCL2L13 CDC42 COQ9 KASH5 LMNA MRM3 MUC1
Entrez ID		55178	2590
HPRD ID		15266	03782
Ensembl ID		ENSG00000171861	ENSG00000143641
Uniprot IDs		Q9HC36	A0A1L7NY50 B7Z6K2 G3V1S6 Q10471
PDB IDs			2FFU 2FFV 4D0T 4D0Z 4D11 5AJN 5AJO 5AJP 5FV9 5NDF 6E7I 6EGS 6NQT
Enriched GO Terms of Interacting Partners?
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