GAD2 and CACNG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GAD2	CACNG1
Description		glutamate decarboxylase 2	calcium voltage-gated channel auxiliary subunit gamma 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Axon Synaptic Vesicle Membrane Anchored Component Of Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane	Integral Component Of Plasma Membrane T-tubule Sarcolemma L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding
	Biological Process	Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Response To Xenobiotic Stimulus Neurotransmitter Biosynthetic Process	Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
Pathways		GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs		Pyridoxal phosphate Glutamic acid	Ergocalciferol Enflurane Ibutilide Diltiazem Spironolactone Lercanidipine Ethanol Fluspirilene Butamben Bioallethrin
Diseases
GWAS		Fasting glucose ( 34059833) Glycated hemoglobin levels ( 34059833) Lean body mass ( 28552196)	Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		48 interacting genes: ABHD5 AGTRAP APOC2 APOC4 ARL13B ARL6IP1 ARMC12 BASP1 BSND CACNG1 CALM1 CMTM5 CPLX4 CYB561D1 DERL1 DERL3 DGAT2L6 DMKN F10 FADS6 FAM114A2 FAM163A GAD1 HIGD1C LDAF1 LIME1 MAL2 MAP3K8 MEST MRM3 PBX3 PLIN3 PRKACA PRKCE RDH10 RHEX RPRM SCAMP1 SDR16C5 SEC22A SMPD2 SPG21 SYCE2 SYNGR3 TMEM120B TMEM128 TNFRSF10D TSPAN33	13 interacting genes: CPLX4 FFAR2 GAD2 GPX8 HSD17B13 LMNA MGST3 MUC1 ODF4 THAP4 TLCD4 TMEM45B VAPA
Entrez ID		2572	786
HPRD ID		11817	00249
Ensembl ID		ENSG00000136750	ENSG00000108878
Uniprot IDs		Q05329 Q5VZ30	Q06432
PDB IDs		1ES0 2OKK
Enriched GO Terms of Interacting Partners?
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