DEFB124 and PGRMC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		DEFB124	PGRMC1
Description		defensin beta 124	progesterone receptor membrane component 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse
	Molecular Function	Protein Binding	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	I-kappaB Kinase/NF-kappaB Signaling Defense Response To Bacterium Innate Immune Response Cellular Response To Peptidoglycan Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production Positive Regulation Of Monocyte Chemotaxis	Heme Biosynthetic Process
Pathways		Beta defensins Defensins	Neutrophil degranulation
Drugs			Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS			Hodgkin's lymphoma ( 34216518)
Interacting Genes		2 interacting genes: NCK2 PGRMC1	21 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A MX1 PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71
Entrez ID		245937	10857
HPRD ID		18759	02338
Ensembl ID		ENSG00000180383	ENSG00000101856
Uniprot IDs		Q8NES8	O00264 Q6IB11
PDB IDs			4X8Y
Enriched GO Terms of Interacting Partners?
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